Technology Process of Imidazo[1,2-a]pyrazin-8(7H)-one, 7-methyl- (9CI)
There total 1 articles about Imidazo[1,2-a]pyrazin-8(7H)-one, 7-methyl- (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
8-oxo-7,8-dihydroimidazo[1,2-a]pyrazine hydrochloride;
With
sodium hydride;
In
DMF (N,N-dimethyl-formamide);
at 60 ℃;
for 0.333333h;
methyl iodide;
at 20 ℃;
for 15h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen / palladium 10% on activated carbon / methanol / 384 h / 2844.39 Torr
2: potassium acetate; triphenylphosphine / palladium diacetate / 2,4-dichlorophenoxyacetic acid dimethylamine / 3 h / 130 °C
With
hydrogen; potassium acetate; triphenylphosphine;
palladium 10% on activated carbon; palladium diacetate;
In
methanol; 2,4-dichlorophenoxyacetic acid dimethylamine;
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
methanol;
for 384h;
under 2844.39 Torr;