8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one

Base Information

Chemical Name:8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one
CAS No.:959571-93-8
Molecular Formula:C₁₉H₁₃BrO₂
Molecular Weight:353.215
Hs Code.:
DSSTox Substance ID:DTXSID50426094
ChEMBL ID:CHEMBL271761

Synonyms:HR-73;959571-93-8;CHEMBL271761;SCHEMBL18134584;DTXSID50426094;8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one;BDBM50193081;HR-73, >=98% (HPLC)

Suppliers and Price of 8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:352.00989
Heavy Atom Count:22
Complexity:418

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(=O)OC2=C1C3=C(C=C2)C=C(C=C3)Br)C4=CC=CC=C4

Technology Process of 8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one

There total 4 articles about 8-Bromo-1,2-dihydro-2-phenyl-3H-naphtho[2,1-b]pyran-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 8-bromo-2-phenyl-3H-naphtho[2,1-b]pyran-3-one

: 959571-93-8
HR-73

Guidance literature:: With pyridine; sodium tetrahydroborate; at 20 ℃; for 0.5h;
DOI:10.1021/ja3096202

Reference yield:

: 103-80-0
phenylacetyl chloride

: 959571-93-8
HR-73

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C

2: sodium tetrahydroborate; pyridine / 0.5 h / 20 °C

With pyridine; sodium tetrahydroborate; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In dichloromethane; water;
DOI:10.1021/ja3096202

Reference yield:

: 103-82-2
phenylacetic acid

: 959571-93-8
HR-73

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride / benzene / 24 h / 20 °C

2: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C

3: sodium tetrahydroborate; pyridine / 0.5 h / 20 °C

With pyridine; sodium tetrahydroborate; oxalyl dichloride; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In dichloromethane; water; benzene;
DOI:10.1021/ja3096202