Technology Process of 1-tert-butyl-3,5-diiodobenzene
There total 3 articles about 1-tert-butyl-3,5-diiodobenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
tert-butylbenzene;
With
[Na4Mg2(2,2,6,6-tetramethylpiperidide)6(n-butyl)2];
In
methyl cyclohexane;
at 60 ℃;
for 12h;
With
iodine;
In
tetrahydrofuran; methyl cyclohexane;
regioselective reaction;
DOI:10.1126/science.1259662
- Guidance literature:
-
With
tert.-butylnitrite;
In
DMF (N,N-dimethyl-formamide);
at 60 ℃;
for 0.166667h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: benzyl triethylammonium dichloroiodate; calcium carbonate / methanol; dichloromethane / 12 h / Reflux
2.1: acetic acid; sulfuric acid; sodium nitrite / 0.5 h / 0 °C / Inert atmosphere
2.2: 24 h / 50 °C / Inert atmosphere
With
sulfuric acid; acetic acid; calcium carbonate; benzyl triethylammonium dichloroiodate; sodium nitrite;
In
methanol; dichloromethane;
DOI:10.1002/anie.201605440
