4-tert-Butyl-2,6-diiodoaniline

Base Information

• Chemical Name: 4-tert-Butyl-2,6-diiodoaniline
• CAS No.: 173282-39-8
• Molecular Formula: C10H13I2N
• Molecular Weight: 401.029
• DSSTox Substance ID: DTXSID90570106
• Nikkaji Number: J2.350.173B
• Wikidata: Q82457450
• Mol file: 173282-39-8.mol

Synonyms:173282-39-8;4-(tert-butyl)-2,6-diiodoaniline;4-tert-Butyl-2,6-diiodoaniline;Benzenamine, 4-(1,1-dimethylethyl)-2,6-diiodo-;SCHEMBL5667106;DTXSID90570106;AC9735;MFCD22042838;SY262667

Chemical Property of 4-tert-Butyl-2,6-diiodoaniline

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 400.91374
• Heavy Atom Count: 13
• Complexity: 164

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1=CC(=C(C(=C1)I)N)I

Technology Process of 4-tert-Butyl-2,6-diiodoaniline

There total 2 articles about 4-tert-Butyl-2,6-diiodoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-tert-Butylaniline (769-92-6) → 4-(tert-butyl)-2,5-diiodoaniline (173282-39-8)

Guidance literature:

With iodine; In chloroform; at 0 ℃; for 2h; Inert atmosphere;

Reference yield: 72.0%

4-tert-Butylaniline (769-92-6) → 4-(tert-butyl)-2,5-diiodoaniline (173282-39-8) + 4-(tert-butyl)-2-iodoaniline (128318-63-8)

Guidance literature:

With calcium carbonate; benzyl triethylammonium dichloroiodate; In methanol; dichloromethane; at 40 ℃;

DOI:10.1021/jo010183n

Reference yield: 99.0%

(R)-1-phenyl-2-propyn-1-ol (4187-87-5,64599-56-0,64937-86-6,61317-73-5) + 4-(tert-butyl)-2,5-diiodoaniline (173282-39-8) → (1S,1'S)-3,3'-(2-amino-5-tert-butyl-1,3-phenylene)bis(1-phenyl-prop-2-yn-1-ol) (1088499-77-7)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ja806723e

upstream raw materials:

4-tert-Butylaniline

Downstream raw materials:

1-(4-(tert-butyl)-2,6-diiodophenyl)-3,3-diethyltriaz-1-ene

4-tert-butyl-2-ethynyl-6-iodoaniline

C₂₄H₂₆I₂N₂

1,3-bis(triisopropylsilylethynyl)-5-tert-butyl-2-iodobenzene