tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Base Information

Chemical Name:tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate
CAS No.:913181-90-5
Molecular Formula:C13H18BrNO3
Molecular Weight:316.195
Hs Code.:2924297099
DSSTox Substance ID:DTXSID70585652
Mol file:913181-90-5.mol

Synonyms:913181-90-5;tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate;N-Boc-2-(4-bromophenyl)-2-hydroxyethanamine;tert-butyl N-[2-(4-bromophenyl)-2-hydroxyethyl]carbamate;tert-Butyl [2-(4-bromophenyl)-2-hydroxyethyl]carbamate;DTXSID70585652;2-Methyl-2-propanyl [2-(4-bromophenyl)-2-hydroxyethyl]carbamate;[2-(4-Bromo-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester;AKOS027383752;CS-16266;CS-0094466;C78576;EN300-6201434;tert-Butyl(2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Suppliers and Price of tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
CARBAMICACID,[2-(4-BROMOPHENYL)-2-HYDROXYETHYL]-,1,1-DIMETHYLETHYLESTER(9Cl) 95
5g
$ 1417.00

ChemScene
tert-Butyl(2-(4-bromophenyl)-2-hydroxyethyl)carbamate
250mg
$ 165.00

ChemScene
tert-Butyl(2-(4-bromophenyl)-2-hydroxyethyl)carbamate
100mg
$ 98.00

ChemScene
tert-Butyl(2-(4-bromophenyl)-2-hydroxyethyl)carbamate
1g
$ 356.00

Apolloscientific
N-Boc-2-(4-bromophenyl)-2-hydroxyethanamine 97%
500mg
$ 457.00

Apolloscientific
N-Boc-2-(4-bromophenyl)-2-hydroxyethanamine 97%
1g
$ 698.00

American Custom Chemicals Corporation
[2-(4-BROMO-PHENYL)-2-HYDROXY-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 495.17

Acrotein
N-Boc-2-(4-bromophenyl)-2-hydroxyethanamine 97%
1g
$ 293.33

Total 8 raw suppliers

Chemical Property of tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Chemical Property:

Boiling Point:438.3±40.0 °C(Predicted)
PKA:12.12±0.46(Predicted)
PSA：58.56000
Density:1.365±0.06 g/cm3(Predicted)
LogP:3.39810
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:315.04701
Heavy Atom Count:18
Complexity:270

Purity/Quality:

98%+ ^*data from raw suppliers

CARBAMICACID,[2-(4-BROMOPHENYL)-2-HYDROXYETHYL]-,1,1-DIMETHYLETHYLESTER(9Cl) 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(C1=CC=C(C=C1)Br)O

Technology Process of tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

There total 5 articles about tert-Butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 339185-70-5
1,1-dimethylethyl [2-(4-bromophenyl)-2-oxoethyl]carbamate

: 913181-90-5
tert-butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃; for 0.5h;
DOI:10.1016/j.jconrel.2020.02.038

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 913181-90-5
tert-butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / triethylamine / CH₂Cl₂ / 18 h / 20 °C

2: 83 percent / sodium borohydride / methanol / 1 h / 20 °C

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.07.043

Reference yield:

: 5467-72-1
α-amino-4-bromoacetophenone hydrochloride

: 913181-90-5
tert-butyl (2-(4-bromophenyl)-2-hydroxyethyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / triethylamine / CH₂Cl₂ / 18 h / 20 °C

2: 83 percent / sodium borohydride / methanol / 1 h / 20 °C

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.07.043