5-Hydroxy-4-azaindole-3-carbaldehyde

Base Information

Chemical Name:5-Hydroxy-4-azaindole-3-carbaldehyde
CAS No.:1027068-77-4
Molecular Formula:C₈H₆N₂O₂
Molecular Weight:162.148
Hs Code.:
DSSTox Substance ID:DTXSID00440280
Wikidata:Q82256553
Mol file:1027068-77-4.mol

Synonyms:1027068-77-4;5-HYDROXY-4-AZAINDOLE-3-CARBALDEHYDE;5-Hydroxy-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde;5-oxo-1,4-dihydropyrrolo[3,2-b]pyridine-3-carbaldehyde;AMY9777;DTXSID00440280;MFCD12962989;PS-18109;CS-0309793;FT-0739574;5-hydroxy-1h-pyrrolo[3,2-b]pyridine-3-carboxaldehyde;5-oxo-4,5-dihydro-1h-pyrrolo[3,2-b]pyridine-3-carboxaldehyde

Suppliers and Price of 5-Hydroxy-4-azaindole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Hydroxy-4-azaindole-3-carbaldehyde
10mg
$ 155.00

Chemenu
5-Hydroxy-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde 95%
1g
$ 425.00

Chemcia Scientific
5-Oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde 95%
0.5 G
$ 405.00

Alichem
5-Hydroxy-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde
1g
$ 464.10

Total 10 raw suppliers

Chemical Property of 5-Hydroxy-4-azaindole-3-carbaldehyde

Chemical Property:

PSA：65.98000
LogP:1.08100
XLogP3:-0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.042927438
Heavy Atom Count:12
Complexity:249

Purity/Quality:

99%, ^*data from raw suppliers

5-Hydroxy-4-azaindole-3-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)NC2=C1NC=C2C=O

Technology Process of 5-Hydroxy-4-azaindole-3-carbaldehyde

There total 3 articles about 5-Hydroxy-4-azaindole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 17288-55-0
3-formyl-5-methoxy-1H-pyrrolo<3,2-b>pyridine

: 1027068-77-4
5-oxo-4,5-dihydro-1H-pyrrolo<3,2-b>pyridine-3-carbaldehyde

Guidance literature:: With hydrogen bromide; In acetic acid; at 100 ℃; for 2h;
DOI:10.1021/jm00013a010

Reference yield:

: 5467-69-6
6-methoxy-3-nitro-2-picoline

: 1027068-77-4
5-oxo-4,5-dihydro-1H-pyrrolo<3,2-b>pyridine-3-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 2.) H₂ / 2.) Pd/C / 1.) reflux, 3 h, 2.) toluene

2: 1.) phosphorus oxychloride, 2.) conc. HCl / 1.) 0 deg C, 1 h, 2.) MeOH, THF, RT, 45 min

3: 94 percent / HBr / acetic acid / 2 h / 100 °C

With hydrogenchloride; hydrogen bromide; hydrogen; trichlorophosphate; palladium on activated charcoal; In acetic acid;
DOI:10.1021/jm00013a010

Reference yield:

: 17288-40-3
5-methoxy-4-aza-1H-indole

: 1027068-77-4
5-oxo-4,5-dihydro-1H-pyrrolo<3,2-b>pyridine-3-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) phosphorus oxychloride, 2.) conc. HCl / 1.) 0 deg C, 1 h, 2.) MeOH, THF, RT, 45 min

2: 94 percent / HBr / acetic acid / 2 h / 100 °C

With hydrogenchloride; hydrogen bromide; trichlorophosphate; In acetic acid;
DOI:10.1021/jm00013a010