2-Chloro-1-(6-methoxyindolin-1-yl)ethanone

Base Information

Chemical Name:2-Chloro-1-(6-methoxyindolin-1-yl)ethanone
CAS No.:793672-17-0
Molecular Formula:C₁₁H₁₂ClNO₂
Molecular Weight:225.675
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70464054
Wikidata:Q82289233
Mol file:793672-17-0.mol

Synonyms:2-Chloro-1-(6-methoxyindolin-1-yl)ethanone;793672-17-0;DTXSID70464054;SB65036;2-chloro-1-(6-methoxyindolin-1-yl)ethan-1-one;Z1813377165

Suppliers and Price of 2-Chloro-1-(6-methoxyindolin-1-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-1-(6-methoxyindolin-1-yl)ethanone 95+%
1g
$ 535.00

Chemenu
2-chloro-1-(6-methoxyindolin-1-yl)ethan-1-one 95%
1g
$ 505.00

American Custom Chemicals Corporation
2-CHLORO-1-(6-METHOXYINDOLIN-1-YL)ETHANONE 95.00%
5MG
$ 499.57

Alichem
2-Chloro-1-(6-methoxyindolin-1-yl)ethanone
1g
$ 436.00

Total 2 raw suppliers

Chemical Property of 2-Chloro-1-(6-methoxyindolin-1-yl)ethanone

Chemical Property:

PSA：29.54000
LogP:1.88810
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:225.0556563
Heavy Atom Count:15
Complexity:247

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-1-(6-methoxyindolin-1-yl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(CCN2C(=O)CCl)C=C1

Technology Process of 2-Chloro-1-(6-methoxyindolin-1-yl)ethanone

There total 2 articles about 2-Chloro-1-(6-methoxyindolin-1-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 7556-47-0
6-methoxy-2,3-dihydro-1H-indole

: 79-04-9
chloroacetyl chloride

: 793672-17-0
2-chloro-1-(6-methoxy-2,3-dihydroindol-1-yl)ethanone

Guidance literature:: With potassium carbonate; In dichloromethane; at 20 ℃; for 6h;
DOI:10.1021/jm049743b

Reference yield:

: 3189-13-7
6-methoxylindole

: 793672-17-0
2-chloro-1-(6-methoxy-2,3-dihydroindol-1-yl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / NaCNBH₃; glacial acetic acid / 3 h / 20 °C

2: 88 percent / K₂CO₃ / CH₂Cl₂ / 6 h / 20 °C

With sodium cyanoborohydride; potassium carbonate; acetic acid; In dichloromethane;
DOI:10.1021/jm049743b