CUSTOMS SYNTHESIS

Base Information

Chemical Name:CUSTOMS SYNTHESIS
CAS No.:1627917-17-2
Molecular Formula:C16H11BO3
Molecular Weight:262.07
Hs Code.:
Mol file:1627917-17-2.mol

Synonyms:CUSTOMS SYNTHESIS;B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid;Benzo[b]naphtho[2,3-d]furan-2-ylboronic acid

Suppliers and Price of CUSTOMS SYNTHESIS

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
Naphtho[2,3-b]benzofuran-2-ylboronicacid 97%
5g
$ 91.00

Ambeed
Naphtho[2,3-b]benzofuran-2-ylboronicacid 97%
1g
$ 27.00

Ambeed
Naphtho[2,3-b]benzofuran-2-ylboronicacid 97%
250mg
$ 11.00

Total 34 raw suppliers

Chemical Property of CUSTOMS SYNTHESIS

Chemical Property:

Boiling Point:529.2±42.0 °C(Predicted)
PKA:8.25±0.30(Predicted)
PSA：53.60000
Density:1.37±0.1 g/cm3(Predicted)
LogP:2.41900

Purity/Quality:

98%,99%, ^*data from raw suppliers

Naphtho[2,3-b]benzofuran-2-ylboronicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Technology Process of CUSTOMS SYNTHESIS

There total 7 articles about CUSTOMS SYNTHESIS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 1627917-16-1
2-bromobenzo[b]naphtho[2,3-d]furan

: 1627917-17-2
benzo[b]naphtho[2,3-d]furan-2-ylboronic acid

Guidance literature:: 2-bromobenzo[b]naphtho[2,3-d]furan; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 12h;

Reference yield:

: 104115-76-6
3-methoxynaphthalen-2-ylboronic acid

: 1627917-17-2
benzo[b]naphtho[2,3-d]furan-2-ylboronic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene / 8 h / Reflux; Inert atmosphere

2.1: boron tribromide / dichloromethane / 24 h / 0 - 20 °C

3.1: potassium carbonate / 1-methyl-pyrrolidin-2-one / 2 h / 120 °C

4.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 0 °C

4.2: 5.17 h / -78 - 20 °C

4.3: 1 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; boron tribromide; sodium carbonate; potassium carbonate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; hexane; dichloromethane; water; toluene;

Reference yield:

: 93-04-9
2-Methoxynaphthalene

: 1627917-17-2
benzo[b]naphtho[2,3-d]furan-2-ylboronic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 4 h / -78 - 20 °C

1.2: 5.17 h / -78 - 20 °C

1.3: 1 h / 20 °C

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene / 8 h / Reflux; Inert atmosphere

3.1: boron tribromide / dichloromethane / 24 h / 0 - 20 °C

4.1: potassium carbonate / 1-methyl-pyrrolidin-2-one / 2 h / 120 °C

5.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 0 °C

5.2: 5.17 h / -78 - 20 °C

5.3: 1 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; boron tribromide; sodium carbonate; potassium carbonate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; hexane; dichloromethane; water; toluene;