2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide

Base Information

Chemical Name:2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide
CAS No.:109322-01-2
Molecular Formula:C₂₄H₁₈ClN₅O₂
Molecular Weight:443.892
Hs Code.:
Mol file:109322-01-2.mol

Synonyms:BRN 5659428;2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide;6H-Indolo(2,3-b)quinoxaline-6-acetic acid, 2-chloro-, ((4-methoxyphenyl)methylene)hydrazide;109322-01-2;C24H18ClN5O2;LS-83951

Suppliers and Price of 2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.39g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:443.1149025
Heavy Atom Count:32
Complexity:685

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=NNC(=O)CN2C3=CC=CC=C3C4=NC5=C(C=CC(=C5)Cl)N=C42
Isomeric SMILES:COC1=CC=C(C=C1)/C=N/NC(=O)CN2C3=CC=CC=C3C4=NC5=C(C=CC(=C5)Cl)N=C42

Technology Process of 2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide

There total 3 articles about 2-Chloro-6H-indolo(2,3-b)quinoxaline-6-acetic acid ((4-methoxyphenyl)methylene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 123-11-5
4-methoxy-benzaldehyde

: 109321-97-3
2-chloroindophenazin-6-acetic acid hydrazide

: 109322-01-2
(2-Chloro-indolo[2,3-b]quinoxalin-6-yl)-acetic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Guidance literature:: With acetic acid; In ethanol; for 4h; Heating;

Reference yield:

: 96340-01-1
2-chloroindophenazine

: 109322-01-2
(2-Chloro-indolo[2,3-b]quinoxalin-6-yl)-acetic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / K₂CO₃ / acetone / 20 h / Heating

2: 90 percent / hydrazine hydrate / ethanol / 6 h / Heating

3: 65 percent / glac.HOAc / ethanol / 4 h / Heating

With potassium carbonate; hydrazine hydrate; acetic acid; In ethanol; acetone;

Reference yield:

: 109321-95-1
6-carbethoxymethyl-2-chloroindophenazine

: 109322-01-2
(2-Chloro-indolo[2,3-b]quinoxalin-6-yl)-acetic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / hydrazine hydrate / ethanol / 6 h / Heating

2: 65 percent / glac.HOAc / ethanol / 4 h / Heating

With hydrazine hydrate; acetic acid; In ethanol;