tert-butyl 4-(3-(4-chlorophenoxy)propanoyl)piperazine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(3-(4-chlorophenoxy)propanoyl)piperazine-1-carboxylate
CAS No.:1246640-00-5
Molecular Formula:C₁₈H₂₅ClN₂O₄
Molecular Weight:368.86
Hs Code.:
Mol file:1246640-00-5.mol

Synonyms:tert-butyl 4-(3-(4-chlorophenoxy)propanoyl)piperazine-1-carboxylate

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Chemical Property of tert-butyl 4-(3-(4-chlorophenoxy)propanoyl)piperazine-1-carboxylate

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Technology Process of tert-butyl 4-(3-(4-chlorophenoxy)propanoyl)piperazine-1-carboxylate

There total 1 articles about tert-butyl 4-(3-(4-chlorophenoxy)propanoyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 3284-79-5
3-(4-chlorophenoxy)propionic acid

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 1246640-00-5
C₁₈H₂₅ClN₂O₄

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 89.0%

: 1246640-00-5
C₁₈H₂₅ClN₂O₄

: 1177209-04-9
C₁₃H₁₇ClN₂O₂

Guidance literature:: With hydrogenchloride; propan-1-ol; at 20 ℃; for 0.5h;

Reference yield:

: 1246640-00-5
C₁₈H₂₅ClN₂O₄

: 1144036-94-1
6-(2-{4-[3-(4-chlorophenoxy)propionyl]piperazin-1-yl}acetyl)-3H-benzoxazol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; propan-1-ol / 0.5 h / 20 °C

2: triethylamine / acetonitrile / 32 h / 20 - 80 °C

With hydrogenchloride; propan-1-ol; triethylamine; In acetonitrile;