Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester

Base Information

Chemical Name:Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester
CAS No.:211746-85-9
Molecular Formula:C24H36N2O15
Molecular Weight:592.54704
Hs Code.:
DSSTox Substance ID:DTXSID60444229
Wikidata:Q82262308
Mol file:211746-85-9.mol

Synonyms:211746-85-9;Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester;(2,5-dioxopyrrolidin-1-yl) 2-[2-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate;BIS(2,5-DIOXOPYRROLIDIN-1-YL) 3,6,9,12,15,18,21-HEPTAOXATRICOSANEDIOATE;DTXSID60444229;CMTBMPFLQYQNDF-UHFFFAOYSA-N;FT-0669137;J-013901

Suppliers and Price of Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
HeptaoxatricosanedioicAcidBis(N-Hydroxysuccinimide)Ester
25mg
$ 155.00

Total 3 raw suppliers

Chemical Property of Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:668.485°C at 760 mmHg
Flash Point:358.087°C
PSA：191.97000
Density:1.371g/cm³
LogP:-1.80720
XLogP3:-2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:26
Exact Mass:592.21156845
Heavy Atom Count:41
Complexity:768

Purity/Quality:

97% ^*data from raw suppliers

HeptaoxatricosanedioicAcidBis(N-Hydroxysuccinimide)Ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)OC(=O)COCCOCCOCCOCCOCCOCCOCC(=O)ON2C(=O)CCC2=O
Uses Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester is used in the preparation of five sialyl Lewis x (sLex) dimers and five sLex carboxylic acids by coupling chemoenzymically synthesized amino-substituted sLex to homo-bifunctional cross-linkers of varying chain length. These compounds should be of importance for the design of new multivalent forms of sLex as well as sLex mimetics as high-affinity selectin ligands.

Technology Process of Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester

There total 4 articles about Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2615-15-8
pentaethylene glycol

: 211746-85-9
(2-{2-[2-(2-{2-[2-(2,5-Dioxo-pyrrolidin-1-yloxycarbonylmethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / aq. KOH, Bu₄NHSO₄ / toluene / 1.) 0 deg C, 10 min, 2.) room temp., 30 min

2: 100 percent / CF₃COOH / CH₂Cl₂ / 2 h / Ambient temperature

3: oxalyl chloride, DMF / CH₂Cl₂ / 1 h / Ambient temperature

4: pyridine / CH₂Cl₂; tetrahydrofuran / 2 h / Ambient temperature

With pyridine; potassium hydroxide; oxalyl dichloride; tetra(n-butyl)ammonium hydrogensulfate; N,N-dimethyl-formamide; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo980350s

Reference yield:

: 83824-29-7,39927-08-7
3,6,9,12,15,18,21-heptaoxatricosane-1,23-dioic acid

: 211746-85-9
(2-{2-[2-(2-{2-[2-(2,5-Dioxo-pyrrolidin-1-yloxycarbonylmethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride, DMF / CH₂Cl₂ / 1 h / Ambient temperature

2: pyridine / CH₂Cl₂; tetrahydrofuran / 2 h / Ambient temperature

With pyridine; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo980350s

Reference yield:

: 211746-80-4
3,6,9,12,15,18,21-heptaoxatricosane-1,23-dioic acid di-tert-butyl ester

: 211746-85-9
(2-{2-[2-(2-{2-[2-(2,5-Dioxo-pyrrolidin-1-yloxycarbonylmethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / CF₃COOH / CH₂Cl₂ / 2 h / Ambient temperature

2: oxalyl chloride, DMF / CH₂Cl₂ / 1 h / Ambient temperature

3: pyridine / CH₂Cl₂; tetrahydrofuran / 2 h / Ambient temperature

With pyridine; oxalyl dichloride; N,N-dimethyl-formamide; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo980350s