alpha-Methylimidazo[1,2-a]pyridine-6-methanamine

Base Information

Chemical Name:alpha-Methylimidazo[1,2-a]pyridine-6-methanamine
CAS No.:1270475-03-0
Molecular Formula:C9H11N3
Molecular Weight:161.20374
Hs Code.:
Mol file:1270475-03-0.mol

Synonyms:alpha-Methylimidazo[1,2-a]pyridine-6-methanamine;1-(imidazo[1,2-a]pyridin-6-yl)ethanamine;1-(H-imidazo[1,2-a]pyridin-6-yl)ethanamine;1-Imidazo[1,2-a]pyridin-6-yl-ethylamine

Suppliers and Price of alpha-Methylimidazo[1,2-a]pyridine-6-methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-Imidazo[1,2-a]pyridin-6-yl-ethylamine 96%
500mg
$ 540.00

J&W Pharmlab
1-Imidazo[1,2-a]pyridin-6-yl-ethylamine 96%
100mg
$ 213.00

J&W Pharmlab
1-Imidazo[1,2-a]pyridin-6-yl-ethylamine 96%
50mg
$ 156.00

J&W Pharmlab
1-Imidazo[1,2-a]pyridin-6-yl-ethylamine 96%
5g
$ 3998.00

AccelPharmtech
a-methyl-Imidazo[1,2-a]pyridine-6-methanamine 97.00%
1G
$ 2640.00

Total 5 raw suppliers

Chemical Property of alpha-Methylimidazo[1,2-a]pyridine-6-methanamine

Chemical Property:

PKA:8.31±0.29(Predicted)
PSA：43.32000
Density:1.22±0.1 g/cm3(Predicted)
LogP:2.05430

Purity/Quality:

99.00% ^*data from raw suppliers

1-Imidazo[1,2-a]pyridin-6-yl-ethylamine 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of alpha-Methylimidazo[1,2-a]pyridine-6-methanamine

There total 6 articles about alpha-Methylimidazo[1,2-a]pyridine-6-methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₉H₉N₅

: 1270475-03-0,1259603-82-1,1259780-63-6
1-(imidazo[1,2-a]pyridin-6-yl)ethanamine

Guidance literature:: With ammonium hydroxide; triphenylphosphine; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm500510f

Reference yield:

: 36052-24-1
methyl 6-aminonicotinoate

: 1270475-03-0,1259603-82-1,1259780-63-6
1-(imidazo[1,2-a]pyridin-6-yl)ethanamine

Guidance literature:: Multi-step reaction with 5 steps

1: water; ethanol / 4 h / Reflux

2: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere

3: tetrahydrofuran / 0 - 20 °C

4: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0 °C

5: ammonium hydroxide; triphenylphosphine / tetrahydrofuran / 20 °C

With ammonium hydroxide; diphenyl phosphoryl azide; isopropylmagnesium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In tetrahydrofuran; ethanol; water;
DOI:10.1021/jm500510f

Reference yield:

: 136117-69-6
methyl 6-imidazo<1,2-a>pyridinecarboxylate

: 1270475-03-0,1259603-82-1,1259780-63-6
1-(imidazo[1,2-a]pyridin-6-yl)ethanamine

Guidance literature:: Multi-step reaction with 4 steps

1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere

2: tetrahydrofuran / 0 - 20 °C

3: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0 °C

4: ammonium hydroxide; triphenylphosphine / tetrahydrofuran / 20 °C

With ammonium hydroxide; diphenyl phosphoryl azide; isopropylmagnesium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In tetrahydrofuran;
DOI:10.1021/jm500510f