Tert-butyl 2-ethylhydrazinecarboxylate

Base Information

• Chemical Name: Tert-butyl 2-ethylhydrazinecarboxylate
• CAS No.: 476362-41-1
• Molecular Formula: C7H16N2O2
• Molecular Weight: 160.216
• Hs Code.: 2925290090
• DSSTox Substance ID: DTXSID20458261
• Nikkaji Number: J2.606.629H
• Wikidata: Q82281464
• Mol file: 476362-41-1.mol

Synonyms:tert-butyl 2-ethylhydrazinecarboxylate;476362-41-1;tert-butyl N-(ethylamino)carbamate;Hydrazinecarboxylic acid, 2-ethyl-, 1,1-dimethylethyl ester (9CI);SCHEMBL2776487;DTXSID20458261;AGBGVIVRTPGQSC-UHFFFAOYSA-N;BUA36241;tert-butyl2-ethylhydrazinecarboxylate;MFCD22380479;SB86446;1-(tert-Butoxycarbonyl)-2-ethylhydrazine;AS-45775;BL009810;CS-0151958;N'-ethylhydrazinecarboxylic acid tert-butyl ester

Chemical Property of Tert-butyl 2-ethylhydrazinecarboxylate

Chemical Property:

• PSA: 53.85000
• LogP: 1.63090
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 160.121177757
• Heavy Atom Count: 11
• Complexity: 129

Purity/Quality:

97% ^*data from raw suppliers

tert-butyl2-ethylhydrazinecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNNC(=O)OC(C)(C)C

Technology Process of Tert-butyl 2-ethylhydrazinecarboxylate

There total 9 articles about Tert-butyl 2-ethylhydrazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

→ N'-ethylhydrazinecarboxylic acid tert-butyl ester (476362-41-1)

Guidance literature:

Reference yield: 82.0%

tert-butyl N-tosyloxycarbamate (105838-14-0) + ethylamine (75-04-7,85404-22-4) → N'-ethylhydrazinecarboxylic acid tert-butyl ester (476362-41-1)

Guidance literature:

With 4-methyl-morpholine; In dichloromethane; at 10 - 20 ℃; for 18h;

DOI:10.1055/s-0030-1261170

Reference yield: 75.0%

tert-butyl 2-ethylidenehydrazinecarboxylate (56572-28-2) → N'-ethylhydrazinecarboxylic acid tert-butyl ester (476362-41-1)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; at -30 - 40 ℃; for 4h;

DOI:10.1016/j.bmcl.2009.08.014

upstream raw materials:

t-butoxycarbonylhydrazine

tert-butyl 2-ethylidenehydrazinecarboxylate

tert-Butyl N-hydroxycarbamate

di-tert-butyl dicarbonate

Downstream raw materials:

tert-butyl 2-((2R,3S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxy-4-phenylbutyl)-2-ethylhydrazinecarboxylate

tert-butyl 2-((2S,3S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxy-4-(3,5-difluorophenyl)butyl)-2-ethylhydrazine-carboxylate

tert-butyl 2-((2S,3S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxy-4-phenylbutyl)-2-ethylhydrazinecarboxylate

tert-butyl 2-benzyl-2-ethyl-1-methylhydrazinecarboxylate