Sulfaclomide

Base Information

Chemical Name:Sulfaclomide
CAS No.:4015-18-3
Molecular Formula:C12H12ClN4NaO2S
Molecular Weight:312.78
Hs Code.:2935009090
UNII:AXA8K5U95M
DSSTox Substance ID:DTXSID20960591
Nikkaji Number:J90.633F
Wikidata:Q27274175
NCI Thesaurus Code:C72643
ChEMBL ID:CHEMBL2107588
Mol file:4015-18-3.mol

Synonyms:5-chloro-2,4-dimethyl-6-sulfanilamidopyrimidine;sulfaclomide;sulfaclomide, monosodium salt;sulfaclomide, sodium salt

Suppliers and Price of Sulfaclomide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-AMINO-N-(5-CHLORO-2,6-DIMETHYL-PYRIMIDIN-4-YL)-BENZENESULFONAMIDE 95.00%
5MG
$ 495.32

Total 5 raw suppliers

Chemical Property of Sulfaclomide

Chemical Property:

Vapor Pressure:4.65E-10mmHg at 25°C
Boiling Point:498.2°Cat760mmHg
Flash Point:255.1°C
PSA：106.35000
Density:1.476g/cm³
LogP:3.86480
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:312.0447745
Heavy Atom Count:20
Complexity:420

Purity/Quality:

99% ^*data from raw suppliers

4-AMINO-N-(5-CHLORO-2,6-DIMETHYL-PYRIMIDIN-4-YL)-BENZENESULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)N)Cl

Technology Process of Sulfaclomide

There total 2 articles about Sulfaclomide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 2858-20-0
5-chloro-2,6-dimethyl-pyrimidin-4-ylamine

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 54951-54-1
N-[4-(dimethylamino-4-ylsulfonyl)phenyl]acetamide

: 63-74-1
sulfanilamide

: 4015-18-3
Sulfaclomid

: 84729-42-0
C₂₂H₂₂ClN₅O₆S₂

: 4049-04-1
4-(4'-Acetylaminobenzensulfonyl)amino-5-chlor-2,6-dimethylpyrimidin

Guidance literature:: With trimethylamine; In dichloromethane; at 33 - 40 ℃; for 10h; Mechanism; Product distribution; further amines;

Reference yield:

: 4015-18-3
Sulfaclomid

Guidance literature:: 5-Chlor-4-amino-2,6-dimethylpyrimidin: 1) 4-Acetaminobenzolsulfonylchlorid/CH2Cl2/Me3N/Et3N (1.5h 30grad, 2h 50-55grad) 2) sd.aq.NaOH;