2858-20-0

Basic information

• Product Name: 4-AMINO-5-CHLORO-2,6-DIMETHYLPYRIMIDINE
• Synonyms: TIMTEC-BB SBB004000;LABOTEST-BB LT00012591;4-AMINO-5-CHLORO-2,6-DIMETHYLPYRIMIDINE;4-AMINO-2-CHLORO-6,7-DIMETHYLPYRIMIDINE
• CAS NO: 2858-20-0
• Molecular Formula: C₆H₈ClN₃
• Molecular Weight: 157.6
• Product Categories: Pyridines, Pyrimidines, Purines and Pteredines;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Building Blocks;C6 to C8;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks
• Mol File: 2858-20-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 164-166 °C(lit.)
• Boiling Point: 257.1 °C at 760 mmHg
• Flash Point: 109.3 °C
• Appearance: /
• Density: 1.284 g/cm³
• Vapor Pressure: 0.0149mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 5.49±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-5-CHLORO-2,6-DIMETHYLPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-5-CHLORO-2,6-DIMETHYLPYRIMIDINE(2858-20-0)
• EPA Substance Registry System: 4-AMINO-5-CHLORO-2,6-DIMETHYLPYRIMIDINE(2858-20-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 2858-20-0(Hazardous Substances Data)

Usage

Uses

4-Amino-5-chloro-2,6-dimethylpyrimidine is suitable reagent employed as a nucleobase standard in the systematic quantitative structure-retention relationship (QSRR) study on pyrimidines between the molecular descriptors (variables) and their chromatographic retention (experimental unit).

General Description

4-Amino-5-chloro-2,6-dimethylpyrimidine (ACDP) is an aminopyrimidine derivative. Its interaction as an electron donor with a σ-electron acceptor, iodine has been studied.

InChI:InChI=1/C6H8ClN3/c1-3-5(7)6(8)10-4(2)9-3/h1-2H3,(H2,8,9,10)

Upstream product

• 121-60-8 p-acetylaminobenzenesulfonyl chloride 

Downstream Products

• 119271-21-5 C₁₄H₁₅ClN₄O₃S 
• 119271-16-8 C₁₃H₁₂Cl₂N₄O₃S 
• 119271-18-0 C₁₄H₁₅ClN₄O₃S 
• 119271-20-4 N-phenylsulfonyl-N'-(5-chloro-2,6-dimethylpyrimidin-4-yl)urea 
• 54951-54-1 N-[4-(dimethylamino-4-ylsulfonyl)phenyl]acetamide 
• 63-74-1 sulfanilamide 
• 4015-18-3 Sulfaclomid 
• 84729-42-0 C₂₂H₂₂ClN₅O₆S₂ 
• 4049-04-1 4-(4'-Acetylaminobenzensulfonyl)amino-5-chlor-2,6-dimethylpyrimidin 
• 1246225-52-4 5-chloro-2,6-dimethyl-N-(2-vinylphenyl)pyrimidin-4-amine 
• 119304-10-8 C₁₃H₁₂ClN₄O₃S^(1-)*Na⁽¹⁺⁾ 

Relevant articles and documents

Studies of the synthesis of sulfonamides: An improved preparation of Sulfaclomid

-