ML314

Base Information

Chemical Name:ML314
CAS No.:1448895-09-7
Molecular Formula:C24H28N4O3
Molecular Weight:420.511
Hs Code.:
Mol file:1448895-09-7.mol

Synonyms:ML314;2-Cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline

Suppliers and Price of ML314

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
ML314 98+%
10mg
$ 326.00

Crysdot
ML314 98+%
5mg
$ 228.00

Crysdot
ML314 98+%
50mg
$ 1172.00

ChemScene
ML314 99.54%
25mg
$ 492.00

ChemScene
ML314 99.54%
50mg
$ 840.00

ChemScene
ML314 99.54%
5mg
$ 144.00

ChemScene
ML314 99.54%
10mg
$ 228.00

Chemenu
2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline 95+%
10mg
$ 305.00

Chemenu
2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline 95+%
50mg
$ 1096.00

Cayman Chemical
ML314 ≥98%
25mg
$ 536.00

Total 6 raw suppliers

Chemical Property of ML314

Chemical Property:

Boiling Point:553.5±50.0 °C(Predicted)
PKA:10.36±0.70(Predicted)
PSA：59.95000
Density:1.245±0.06 g/cm3(Predicted)
LogP:3.98960

Purity/Quality:

97% ^*data from raw suppliers

ML314 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ML314

There total 3 articles about ML314 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1448676-37-6
4-chloro-2-cyclopropyl-6,7-dimethoxy-quinazoline

: 5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride

: 1448895-09-7
2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline

Guidance literature:: With potassium carbonate; In 1,4-dioxane; at 80 ℃; for 1.5h; Microwave irradiation; Inert atmosphere;
DOI:10.1021/ml400176n

Reference yield:

: 26759-46-6
methyl 2-amino-4,5-dimethoxybenzoate

: 1448895-09-7
2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / 1,4-dioxane / 15 h / 100 °C / Inert atmosphere

2: trichlorophosphate / 15 h / 110 °C / Inert atmosphere

3: potassium carbonate / 1,4-dioxane / 1.5 h / 80 °C / Microwave irradiation; Inert atmosphere

With hydrogenchloride; potassium carbonate; trichlorophosphate; In 1,4-dioxane;
DOI:10.1021/ml400176n

Reference yield:

: 630422-37-6
2-cyclopropyl-6,7-dimethoxyquinazolin-4-ol

: 1448895-09-7
2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 15 h / 110 °C / Inert atmosphere

2: potassium carbonate / 1,4-dioxane / 1.5 h / 80 °C / Microwave irradiation; Inert atmosphere

With potassium carbonate; trichlorophosphate; In 1,4-dioxane;
DOI:10.1021/ml400176n