5-(2-chlor-phenyl)-valeriansaeure

Base Information

• Chemical Name: 5-(2-chlor-phenyl)-valeriansaeure
• CAS No.: 100126-82-7
• Molecular Formula: C11H13ClO2
• Molecular Weight: 212.67272
• Mol file: 100126-82-7.mol

Synonyms:5-(2-chlor-phenyl)-valeriansaeure

Chemical Property of 5-(2-chlor-phenyl)-valeriansaeure

Chemical Property:

• Boiling Point: 166 - 167 °C (1 mmHg)
• PSA: 37.30000
• LogP: 3.13740

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(2-chlor-phenyl)-valeriansaeure

There total 5 articles about 5-(2-chlor-phenyl)-valeriansaeure which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H11ClO2 → 5-(2-Chlor-phenyl)-valeriansaeure (100126-82-7)

Guidance literature:

With hydrogen; In benzene; at 20 ℃;

DOI:10.1111/bph.14874

Reference yield:

4-(2-chlorophenyl)butan-1-ol (90875-76-6) → 5-(2-Chlor-phenyl)-valeriansaeure (100126-82-7)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃

2: (i) Mg, (ii) /BRN= 1900390/

With phosphorus tribromide;

DOI:10.1021/jo01034a013

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + 4--butylbromid (91130-24-4) → 5-(2-Chlor-phenyl)-valeriansaeure (100126-82-7)

Guidance literature:

Multistep reaction; (i) Mg, (ii) /BRN= 1900390/;

DOI:10.1021/jo01034a013

upstream raw materials:

3-(2-chlorophenyl)propylmalonic acid diethyl ester

carbon dioxide

4--butylbromid

4-(2-chlorophenyl)butan-1-ol

Downstream raw materials:

5-(2-chlorophenyl)pentan-1-ol

1-butyl-2-chlorobenzene

Refernces