2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE

Base Information

• Chemical Name: 2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE
• CAS No.: 75295-62-4
• Molecular Formula: C13H9BrO
• Molecular Weight: 261.118
• Mol file: 75295-62-4.mol

Synonyms:2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE

Chemical Property of 2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE

Chemical Property:

• PSA: 17.07000
• LogP: 3.92860

Purity/Quality:

95+% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE

There total 1 articles about 2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 2,3-dibromobenzene (583-53-9) → 2′-bromo-[1,1′-biphenyl]-2-carbaldehyde (75295-62-4) + ortho-bromobenzaldehyde (6630-33-7)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, Et₂O, hexane, -110 deg C, 30 min, 2.) THF, Et₂O, hexane, -110 deg C, 120 min;

DOI:10.1016/S0022-328X(00)90287-0

Reference yield: 95.0%

2′-bromo-[1,1′-biphenyl]-2-carbaldehyde (75295-62-4) + ethylene glycol (107-21-1) → dioxolane derivative of 2-bromobiphenyl-2'-carbaldehyde (400750-97-2)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; Reflux; Inert atmosphere;

DOI:10.1002/ejic.201100466

Reference yield: 92.0%

2′-bromo-[1,1′-biphenyl]-2-carbaldehyde (75295-62-4) + benzylamine (100-46-9) → 5-benzylphenanthridin-5-ium bromide (64433-61-0)

Guidance literature:

With copper dichloride; In ethylene glycol; at 100 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00269

upstream raw materials:

N,N-dimethyl-formamide

2,3-dibromobenzene

Downstream raw materials:

4-[(4-methoxyphenyl)methoxy]-1-[(2'-bromobiphenyl)-2-yl]-2-butyn-1-ol

dioxolane derivative of 2-bromobiphenyl-2'-carbaldehyde

6H-benzo[c]chromen-6-one

N-(4-methoxyphenyl)-9H-fluoren-9-amine

Refernces