Phenanthridinium, 5-(phenylmethyl)-, bromide

Base Information

• Chemical Name: Phenanthridinium, 5-(phenylmethyl)-, bromide
• CAS No.: 64433-61-0
• Molecular Formula: C20H16N.Br
• Molecular Weight: 350.258
• Mol file: 64433-61-0.mol

Synonyms:

Chemical Property of Phenanthridinium, 5-(phenylmethyl)-, bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenanthridinium, 5-(phenylmethyl)-, bromide

There total 4 articles about Phenanthridinium, 5-(phenylmethyl)-, bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2′-bromo-[1,1′-biphenyl]-2-carbaldehyde (75295-62-4) + benzylamine (100-46-9) → 5-benzylphenanthridin-5-ium bromide (64433-61-0)

Guidance literature:

With copper dichloride; In ethylene glycol; at 100 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00269

Reference yield:

phenanthridine (229-87-8) + benzyl bromide (100-39-0) → 5-benzylphenanthridin-5-ium bromide (64433-61-0)

Guidance literature:

In ethanol;

DOI:10.1021/ja00364a026

Reference yield:

1-Bromo-2-iodobenzene (583-55-1) → 5-benzylphenanthridin-5-ium bromide (64433-61-0)

Guidance literature:

Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; tripotassium phosphate "n" hydrate / toluene / 12 h / 100 °C / Schlenk technique; Inert atmosphere

2: copper dichloride / ethylene glycol / 24 h / 100 °C / Schlenk technique; Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; tripotassium phosphate "n" hydrate; copper dichloride; In ethylene glycol; toluene;

DOI:10.1021/acs.orglett.6b00269

upstream raw materials:

phenanthridine

benzyl bromide

3,10-dimethyl-5-deazaisoalloxazine

2′-bromo-[1,1′-biphenyl]-2-carbaldehyde

Downstream raw materials:

6(5H)-phenanthridinone

5-benzyl-5,6-dihydrophenanthridine

5-(benzyl)phenanthridin-6(5H)-one

3,10-dimethyl-5-deazaisoalloxazine