1,1'-(2-Fluorocyclopropylidene)bisbenzene

Base Information

• Chemical Name: 1,1'-(2-Fluorocyclopropylidene)bisbenzene
• CAS No.: 56701-13-4
• Molecular Formula: C15H13F
• Molecular Weight: 212.267
• Mol file: 56701-13-4.mol

Synonyms:1,1'-(2-Fluorocyclopropylidene)bisbenzene

Chemical Property of 1,1'-(2-Fluorocyclopropylidene)bisbenzene

Chemical Property:

• PSA: 0.00000
• LogP: 3.71450

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1'-(2-Fluorocyclopropylidene)bisbenzene

There total 5 articles about 1,1'-(2-Fluorocyclopropylidene)bisbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-fluoro-2,2-diphenyl-1-phenylsulfonylcyclopropane (1609090-46-1) → (2-fluorocyclopropane-1,1-diyl)dibenzene (56701-13-4)

Guidance literature:

With magnesium; mercury dichloride; In methanol; at 50 ℃; for 3.5h; Inert atmosphere;

DOI:10.1246/cl.130570

Reference yield: 75.0%

(2-bromo-2-fluorocyclopropane-1,1-diyl)dibenzene (64859-37-6) → (2-fluorocyclopropane-1,1-diyl)dibenzene (56701-13-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 70 ℃; for 4h; Inert atmosphere;

DOI:10.1039/d0cc06004f

Reference yield:

C21H17FS (116109-48-9) → (2-fluorocyclopropane-1,1-diyl)dibenzene (56701-13-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane; chloroform / 7 h / -20 - 20 °C

2: 3-chloro-benzenecarboperoxoic acid / chloroform / 16 h / -20 - 20 °C / Inert atmosphere

3: magnesium; mercury dichloride / methanol / 3.5 h / 50 °C / Inert atmosphere

With magnesium; 3-chloro-benzenecarboperoxoic acid; mercury dichloride; In methanol; dichloromethane; chloroform;

DOI:10.1246/cl.130570

upstream raw materials:

C₂₁H₁₇FS

1-fluoro-2,2-diphenyl-1-phenylsulfonylcyclopropane

(2-bromo-2-fluorocyclopropane-1,1-diyl)dibenzene

1,1-Diphenylethylene

Refernces

• 1、 Kirihara, Masayuki,Ogata, Tomomi,Itou, Atsushi,Naito, Sayuri,Kishida, Mari,Yamazaki, Kento,Tabata, Hidetsugu,Takahashi, Hideyo. "Synthesis of monofluoromethylcyclopropanes from alkenes without using freons: Novel synthesis of chlorofluoromethyl phenyl sulfide and its application in cyclopropanation". . p. 1377 - 1379. Retrieved 2013/11/19.