Amino-cyclopropyl-acetic acid methyl ester

Base Information

• Chemical Name: Amino-cyclopropyl-acetic acid methyl ester
• CAS No.: 768356-83-8
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.159
• Mol file: 768356-83-8.mol

Synonyms:Amino-cyclopropyl-acetic acid methyl ester;methyl-2-amino-2-cyclopropylacetate

Chemical Property of Amino-cyclopropyl-acetic acid methyl ester

Chemical Property:

• Boiling Point: 162.0±13.0 °C(Predicted)
• PKA: 7?+-.0.50(Predicted)
• PSA: 52.32000
• Density: 1.147±0.06 g/cm3(Predicted)
• LogP: 0.59700

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-amino-2-cyclopropylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Amino-cyclopropyl-acetic acid methyl ester

There total 3 articles about Amino-cyclopropyl-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + (S)-2-amino-2-cyclopropyl acetic acid (15785-26-9) → methyl 2-amino-2-cyclopropylacetate (768356-83-8)

Guidance literature:

With thionyl chloride; In methanol; at 20 ℃; for 20h;

DOI:10.1002/adsc.200606038

Reference yield:

cyclopropyl-hydroxyiminoacetic acid (936097-37-9) → methyl 2-amino-2-cyclopropylacetate (768356-83-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / Zn / acetic acid / 0.5 h / 20 - 30 °C

2: SOCl₂ / methanol / 20 h / 20 °C

With thionyl chloride; zinc; In methanol; acetic acid;

DOI:10.1002/adsc.200606038

Reference yield:

Cyclopropyl methyl ketone (765-43-5) → methyl 2-amino-2-cyclopropylacetate (768356-83-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 74 percent / KMnO₄; Na₂CO₃ / H₂O / 50 h / 50 °C

2: 99 percent / NH₂OH*HCl / H₂O / 0.33 h / 45 °C

3: 93 percent / Zn / acetic acid / 0.5 h / 20 - 30 °C

4: SOCl₂ / methanol / 20 h / 20 °C

With potassium permanganate; thionyl chloride; hydroxylamine hydrochloride; sodium carbonate; zinc; In methanol; water; acetic acid;

DOI:10.1002/adsc.200606038

upstream raw materials:

methanol

(S)-2-amino-2-cyclopropyl acetic acid

cyclopropyl-hydroxyiminoacetic acid

Cyclopropyl methyl ketone

Downstream raw materials:

methyl 2-(N-benzyloxycarbonylamino)-2-cyclopropylacetate

(2S)-2-[[(tert-butoxy)carbonyl]amino]-2-cyclopropylacetic acid

(S)-2-amino-2-cyclopropylacetic acid

methyl 2-(N-tert-butoxycarbonylamino)-2-cyclopropylacetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 768356-83-8 Amino-cyclopropyl-acetic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send