10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Base Information

• Chemical Name: 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide
• CAS No.: 194235-38-6
• Molecular Formula: C₂₁H₂₄BF₂N₃
• Molecular Weight: 367.249
• Mol file: 194235-38-6.mol

Synonyms:10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Chemical Property of 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

There total 8 articles about 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

2,4-dimethyl-1H-pyrrole (625-82-1) + boron trifluoride diethyl etherate (109-63-7) + 4-dimethylamino-benzaldehyde (100-10-7) → 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (194235-38-6)

Guidance literature:

2,4-dimethyl-1H-pyrrole; 4-dimethylamino-benzaldehyde; With trifluoroacetic acid; In dichloromethane; at 20 ℃;

boron trifluoride diethyl etherate; With chloranil; triethylamine; In dichloromethane; at 0 ℃; for 17h;

DOI:10.1142/S1088424619501773

Reference yield: 37.0%

2,4-dimethyl-1H-pyrrole (625-82-1) + trifluoroborane diethyl ether (109-63-7) + 4-dimethylamino-benzaldehyde (100-10-7) + trifluoroacetic acid (76-05-1) → 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (194235-38-6)

Guidance literature:

In dichloromethane; (N2); stirring (room temp.), addn. of dichlorodicyanobenzoquinone in CH2Cl2, stirring (15 min), addn. of N-ethyl-N,N-diisopropylamine and BF3*Et2O, stirring (30 min); washing (H2O), evapn., chromy. (SiO2, CH2Cl2), recrystn. (CHCl3/hexane);elem. anal.;

DOI:10.1021/jp982701c

Reference yield:

C21H25N3 (1253395-80-0) → 10-(4-(dimethylamino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (194235-38-6)

Guidance literature:

With boron trifluoride diethyl etherate; triethylamine; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.04.137

upstream raw materials:

2,4-dimethyl-1H-pyrrole

trifluoroborane diethyl ether

4-dimethylamino-benzaldehyde

trifluoroacetic acid