ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate

Base Information

• Chemical Name: ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate
• CAS No.: 783365-87-7
• Molecular Formula: C₂₄H₁₈F₄N₂O₃S₂
• Molecular Weight: 522.544
• Mol file: 783365-87-7.mol

Synonyms:ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate

Chemical Property of ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate

There total 3 articles about ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

ethyl α<(N,N-dimethylamino)methylene>-2,3,4,5-tetrafluoro-β-oxobenzenepropanoate (138998-47-7) + 2-Aminophenyl disulfide (1141-88-4) → ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate (783365-87-7)

Guidance literature:

In acetonitrile; for 3h;

Reference yield:

ethyl 3-(2,3,4,5-tetrafkuorophenyl)-3-oxopropanoate (94695-50-8) → ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate (783365-87-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride / 0.5 h

2: acetonitrile / 3 h

With acetic anhydride; In acetonitrile;

Reference yield:

2,3,4,5-tetrafluorobenzoyl chloride (94695-48-4) → ethyl 2-(2',3',4',5'-tetrafluorobenzoyl)-3-(N-aminobenzyldisulfide)-prop-2-enoate (783365-87-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine; magnesium chloride / acetonitrile / 2.5 h / 10 - 15 °C

1.2: 16 h / 0 - 20 °C

2.1: acetic anhydride / 0.5 h

3.1: acetonitrile / 3 h

With acetic anhydride; triethylamine; magnesium chloride; In acetonitrile;

upstream raw materials:

ethyl α<(N,N-dimethylamino)methylene>-2,3,4,5-tetrafluoro-β-oxobenzenepropanoate

2-Aminophenyl disulfide

ethyl 3-(2,3,4,5-tetrafkuorophenyl)-3-oxopropanoate

2,3,4,5-tetrafluorobenzoyl chloride