Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate

Base Information Edit

Chemical Name:Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate
CAS No.:94695-50-8
Molecular Formula:C11H8F4O3
Molecular Weight:264.176
Hs Code.:29183000
European Community (EC) Number:700-167-6
DSSTox Substance ID:DTXSID70344983
Nikkaji Number:J340.036K
Wikidata:Q72477278
Mol file:94695-50-8.mol

Synonyms:94695-50-8;Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate;Ethyl 2,3,4,5-tetrafluorobenzoylacetate;ethyl 3-(2,3,4,5-tetrafluorophenyl)-3-oxopropanoate;Ethyl (2,3,4,5-Tetrafluorobenzoyl)acetate;(2,3,4,5-Tetrafluorobenzoyl)acetic Acid Ethyl Ester;EC 700-167-6;2,3,4,5-Tetrafluorobenzoylacetic Acid Ethyl Ester;Ethyl 3-oxo-(2,3,4,5-tetrafluorophenyl)propanoate;MFCD00523020;ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propionate;2,3,4,5-tetrafluorobenzoylacetic acid, ethyl ester;ethyl 2,3,4,5-tetrafluoro-beta-oxobenzenepropanoate;SCHEMBL1185918;DTXSID70344983;3-oxo-3-(2,3,4,5-tetrafluoro-phenyl)-propionic acid ethyl ester;BCP13423;AKOS015838707;AC-7594;Ethyl (2345-Tetrafluorobenzoyl)acetate;AS-33243;SY057196;ethyl 2,3,4,5-tetrafluorobenzoyl-acetate;E0759;FT-0642281;EN300-1725192;ethyl alpha-(2,3,4,5-tetrafluorobenzoyl)acetate;ethyl-(2',3',4',5'-tetrafluorobenzoyl)-ethanoate;2-(2,3,4,5-tetrafluorobenzoyl)acetic acid, ethyl ester;Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate #;2,3,4,5-tetrafluoro-beta-oxobenzenepropanoic acid, ethyl ester;2,3,4,5-tetrafluorobeta-oxo-benzenepropanoic acid, ethyl ester;2,3,4,5-tetrafluoro-beta-oxo-benzenepropanoic acid, ethyl ester;2,3,4,5-tetrafluoro-beta-oxo-benzeneproprionic acid, ethyl ester;3-Oxo-3-(2,3,4,5-tetrafluorophenyl)propionic Acid Ethyl Ester;3-Oxo-3-(2,3,4,5-tetrafluorophenyl)propionic acid, ethyl ester

Suppliers and Price of Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ethyl 2-
500mg
$ 382.00

Usbiological
Ethyl 2-
50mg
$ 319.00

Usbiological
Ethyl 2-
100mg
$ 319.00

Usbiological
Ethyl 2-
5g
$ 319.00

Usbiological
Ethyl 2-
25mg
$ 312.00

Usbiological
Ethyl 2-
25mg
$ 312.00

Usbiological
Ethyl 2-
100mg
$ 305.00

Usbiological
Ethyl 2-
25mg
$ 305.00

Usbiological
Ethyl 2-
500mg
$ 305.00

Usbiological
Ethyl 2-
100mg
$ 305.00

Total 82 raw suppliers

Chemical Property of Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate Edit

Chemical Property:

Vapor Pressure:0.00259mmHg at 25°C
Melting Point:41-44 °C
Refractive Index:1.456
Boiling Point:286.7 °C at 760 mmHg
PKA:10.51±0.50(Predicted)
Flash Point:123.3 °C
PSA：43.37000
Density:1.384 g/cm³
LogP:2.37890
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:DMSO, Methanol
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:264.04095676
Heavy Atom Count:18
Complexity:323

Purity/Quality:

99%min ^*data from raw suppliers

Ethyl 2- ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C1=CC(=C(C(=C1F)F)F)F
Uses Ethyl 2,3,4,5-tetrafluorobenzoyl acetate is a fluorinated benzoylacetate used as a synthetic reagent in the preparation of antibacterial and potential antitumor agents. 2,3,4,5-Tetrafluorobenzoylacetic Acid Ethyl Ester is a fluorinated benzoylacetate used as a synthetic reagent in the preparation of antibacterial and potential antitumor agents.

Technology Process of Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate

There total 14 articles about Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 6148-64-7
ethyl potassium malonate

: 94695-48-4
2,3,4,5-tetrafluorobenzoyl chloride

: 94695-50-8
ethyl 3-(2,3,4,5-tetrafkuorophenyl)-3-oxopropanoate

Guidance literature:: ethyl potassium malonate; With triethylamine; magnesium chloride; In acetonitrile; at 10 - 15 ℃; for 2.5h;

2,3,4,5-tetrafluorobenzoyl chloride; With triethylamine; In acetonitrile; at 0 - 20 ℃; for 16h;