2-Azaspiro(4.5)decane-2-propanamine, N,N-dimethyl-8,8-dipropyl-

Base Information

Chemical Name:2-Azaspiro(4.5)decane-2-propanamine, N,N-dimethyl-8,8-dipropyl-
CAS No.:123018-34-8
Molecular Formula:C₂₀H₄₀N₂
Molecular Weight:308.551
Hs Code.:
UNII:93772T99MP
DSSTox Substance ID:DTXSID50924348
Nikkaji Number:J351.763B
Wikidata:Q27271570
ChEMBL ID:CHEMBL101018
Mol file:123018-34-8.mol

Synonyms:N,N-dimethyl-8,8-dipropyl-2-azaspiro(4.5)decane-2-propanamide;N,N-dimethyl-8,8-dipropyl-2-azaspiro-(4.5)decane-2-propanamine;SK and F 105685;SK and F 105685 dihydrochloride;SK and F-105685;SKF 105685

Suppliers and Price of 2-Azaspiro(4.5)decane-2-propanamine, N,N-dimethyl-8,8-dipropyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Azaspiro(4.5)decane-2-propanamine, N,N-dimethyl-8,8-dipropyl-

Chemical Property:

Vapor Pressure:1.62E-05mmHg at 25°C
Boiling Point:364.9°Cat760mmHg
Flash Point:154.8°C
Density:0.92g/cm³
XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:8
Exact Mass:308.319149284
Heavy Atom Count:22
Complexity:308

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1(CCC2(CC1)CCN(C2)CCCN(C)C)CCC

Technology Process of 2-Azaspiro(4.5)decane-2-propanamine, N,N-dimethyl-8,8-dipropyl-

There total 7 articles about 2-Azaspiro(4.5)decane-2-propanamine, N,N-dimethyl-8,8-dipropyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 130065-95-1
2-<3-(dimethylamino)propyl>-8,8-dipropyl-2-azaspiro<4.5>decane-1,3-dione

: 123018-34-8
N,N-dimethyl-8,8-dipropyl-2-azaspiro [4,5] decane-2-propanamine dihydrochloride

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 3h;
DOI:10.1021/jm00173a010

Reference yield:

: 60729-41-1
4,4-dipropylcyclohex-2-en-1-one

: 123018-34-8
N,N-dimethyl-8,8-dipropyl-2-azaspiro [4,5] decane-2-propanamine dihydrochloride

Guidance literature:: Multi-step reaction with 7 steps

1: 98 percent / H₂ / 10percent Pd/C / ethyl acetate / 5 h / 2585.7 Torr / Ambient temperature

2: 89 percent / ammonium acetate, acetic acid / toluene / Heating

3: ethanol; H₂O / 5 h / Heating

4: acetic acid, hydrochloric acid, H₂O / 84 h / Heating

5: 89 percent / acetic anhydride / 4 h / Heating

6: 100 percent / Heating

7: 95 percent / LiAlH₄ / diethyl ether / 3 h

With ammonium acetate; hydrogenchloride; lithium aluminium tetrahydride; water; hydrogen; acetic anhydride; acetic acid; palladium on activated charcoal; In diethyl ether; ethanol; water; ethyl acetate; toluene;
DOI:10.1021/jm00173a010

Reference yield:

: 123018-62-2
4,4-di-n-propylcyclohexanone

: 123018-34-8
N,N-dimethyl-8,8-dipropyl-2-azaspiro [4,5] decane-2-propanamine dihydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: 89 percent / ammonium acetate, acetic acid / toluene / Heating

2: ethanol; H₂O / 5 h / Heating

3: acetic acid, hydrochloric acid, H₂O / 84 h / Heating

4: 89 percent / acetic anhydride / 4 h / Heating

5: 100 percent / Heating

6: 95 percent / LiAlH₄ / diethyl ether / 3 h

With ammonium acetate; hydrogenchloride; lithium aluminium tetrahydride; water; acetic anhydride; acetic acid; In diethyl ether; ethanol; water; toluene;
DOI:10.1021/jm00173a010