2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

Base Information

Chemical Name:2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine
CAS No.:869891-45-2
Molecular Formula:C₁₇H₂₁ClN₂O₂
Molecular Weight:320.819
Hs Code.:

Synonyms:2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

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Chemical Property of 2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

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Technology Process of 2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

There total 4 articles about 2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 869891-36-1
2,4-dichloro-5-(5-isopropyl-2-methyl-phenoxymethyl)-6-methyl-pyrimidine

: 124-41-4
sodium methylate

: 869891-45-2
2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

Guidance literature:: In methanol; at -5 ℃; for 1h;

Reference yield:

: 626-48-2
6-Methyluracil

: 869891-45-2
2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydroxide / water / 0.17 h / 20 °C

1.2: 3 h

2.1: tributyl-amine / trichlorophosphate / 7 h / 90 °C / Heating / reflux

3.1: potassium tert-butylate / tetrahydrofuran; ISOPROPYLAMIDE / 40.33 h / 0 - 20 °C

4.1: methanol / 1 h / -5 °C

With sodium hydroxide; tributyl-amine; potassium tert-butylate; In tetrahydrofuran; methanol; ISOPROPYLAMIDE; water; trichlorophosphate;

Reference yield:

: 16768-43-7
2,4-Dichloro-5-chloromethyl-6-methyl-pyrimidine

: 869891-45-2
2-chloro-5-[(5-isopropyl-2-methylphenoxy)methyl]-4-methoxy-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran; ISOPROPYLAMIDE / 40.33 h / 0 - 20 °C

2: methanol / 1 h / -5 °C

With potassium tert-butylate; In tetrahydrofuran; methanol; ISOPROPYLAMIDE;