Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester
• CAS No.: 168965-81-9
• Molecular Formula: C₂₄H₃₁NO₅S
• Molecular Weight: 445.58
• Mol file: 168965-81-9.mol

Synonyms:Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester

Chemical Property of Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester

There total 3 articles about Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Methoxycarbonyl-4-nitrobenzoic acid (64152-09-6) → Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester (168965-81-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 91 percent / BH₃*methyl sulfide / tetrahydrofuran / 5 h / Heating

2: 94 percent / PCC, neutral activity I Al₂O₃ / CH₂Cl₂ / 18 h / 0 °C

3: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 40 min, 2.) THF, hexane, 0 deg C, 3.5 h

4: 82 percent / LiBH₄ / tetrahydrofuran / 17 h / 0 - 20 °C

5: NaH / toluene / 2 h / Ambient temperature

With aluminum oxide; lithium borohydride; n-butyllithium; dimethylsulfide borane complex; sodium hydride; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1021/jm970704s

Reference yield:

5-((Z)-Dec-1-enyl)-2-nitro-benzoic acid methyl ester (168965-79-5) → Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester (168965-81-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / LiBH₄ / tetrahydrofuran / 17 h / 0 - 20 °C

2: NaH / toluene / 2 h / Ambient temperature

With lithium borohydride; sodium hydride; In tetrahydrofuran; toluene;

DOI:10.1021/jm970704s

Reference yield:

p-toluenesulfonyl chloride (98-59-9) + [5-((Z)-Dec-1-enyl)-2-nitro-phenyl]-methanol (168965-80-8) → Toluene-4-sulfonic acid 5-((Z)-dec-1-enyl)-2-nitro-benzyl ester (168965-81-9)

Guidance literature:

With sodium hydride; In toluene;

DOI:10.1248/cpb.45.424

upstream raw materials:

p-toluenesulfonyl chloride

[5-((Z)-Dec-1-enyl)-2-nitro-phenyl]-methanol

3-Methoxycarbonyl-4-nitrobenzoic acid

5-((Z)-Dec-1-enyl)-2-nitro-benzoic acid methyl ester

Downstream raw materials:

2-Acetylamino-2-[5-((Z)-dec-1-enyl)-2-nitro-benzyl]-malonic acid diethyl ester

2-Amino-3-[5-((Z)-dec-1-enyl)-2-nitro-phenyl]-propionic acid

[2-(2-Amino-5-decyl-phenyl)-1-hydroxymethyl-ethyl]-carbamic acid tert-butyl ester

[2-(5-Decyl-2-methylamino-phenyl)-1-hydroxymethyl-ethyl]-carbamic acid tert-butyl ester