N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide

Base Information

Chemical Name:N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide
CAS No.:42045-95-4
Molecular Formula:C₂₃H₃₀N₂O
Molecular Weight:350.504
Hs Code.:
DSSTox Substance ID:DTXSID90962229

Synonyms:BRN 0495143;N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide;Propanamide, N-(2,5-dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenyl-;42045-95-4;DTXSID90962229;N-(1-benzyl-2,5-dimethylpiperidin-4-yl)-N-phenylpropanamide;LS-119216

Suppliers and Price of N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide

Chemical Property:

Vapor Pressure:1.07E-08mmHg at 25°C
Boiling Point:461.4°C at 760 mmHg
Flash Point:176.8°C
Density:1.064g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:350.235813585
Heavy Atom Count:26
Complexity:440

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)N(C1CC(N(CC1C)CC2=CC=CC=C2)C)C3=CC=CC=C3

Technology Process of N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide

There total 5 articles about N-(2,5-Dimethyl-1-(phenylmethyl)-4-piperidinyl)-N-phenylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 104053-57-8
(1-Benzyl-2,5-dimethyl-piperidin-4-yl)-phenyl-amine

: 79-03-8
propionyl chloride

: 42045-95-4
N-(1-benzyl-2,5-dimethyl-piperidin-4-yl)-N-phenyl-propionamide

Guidance literature:: With triethylamine; In benzene; for 7h; Ambient temperature;
DOI:10.1007/BF00758289

Reference yield:

: 63791-75-3
1-benzyl-2,5-dimethyl-piperidin-4-one

: 42045-95-4
N-(1-benzyl-2,5-dimethyl-piperidin-4-yl)-N-phenyl-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / glacial acetic acid / toluene / Heating

2: 86 percent / sodium borohydride / methanol / 0.5 h / 20 °C

3: 70 percent / triethylamine / benzene / 7 h / Ambient temperature

With sodium tetrahydroborate; acetic acid; triethylamine; In methanol; toluene; benzene;
DOI:10.1007/BF00758289

Reference yield:

: 113556-35-7
N-(1-Benzyl-2,5-dimethylpiperidylidene-4)aniline

: 42045-95-4
N-(1-benzyl-2,5-dimethyl-piperidin-4-yl)-N-phenyl-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / sodium borohydride / methanol / 0.5 h / 20 °C

2: 70 percent / triethylamine / benzene / 7 h / Ambient temperature

With sodium tetrahydroborate; triethylamine; In methanol; benzene;
DOI:10.1007/BF00758289