phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Base Information

Chemical Name:phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate
CAS No.:1073633-91-6
Molecular Formula:C₂₉H₃₂N₆O₆
Molecular Weight:560.61
Hs Code.:

phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Synonyms:phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Suppliers and Price of phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

There total 8 articles about phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 1073634-29-3
phenylmethyl 6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

: 1073633-89-2
1,1-dimethylethyl (2-iodo-5,6,7,8-tetrahydro-6-quinazolinyl)carbamate

: 1073633-91-6
phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Guidance literature:: With potassium carbonate; copper(l) iodide; rac-diaminocyclohexane; In 1,4-dioxane; at 125 ℃; for 10h;

Reference yield:

: 38533-61-8
2-chloro-6-methoxy-3-nitropyridine

: 1073633-91-6
phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Guidance literature:: Multi-step reaction with 6 steps

1: ammonia / methanol / 18 h / 65 °C

2: hydrogen / palladium on activated charcoal / ethanol / 20 °C / 760.05 Torr

3: potassium carbonate / acetonitrile / 20 °C

4: potassium tert-butylate / tetrahydrofuran / 1.5 - 2 h / 0 - 20 °C

5: sodium hydrogencarbonate / water; ethyl acetate / 0.75 h / 20 °C

6: potassium carbonate / copper(l) iodide; rac-diaminocyclohexane / 1,4-dioxane / 10 h / 125 °C

With potassium tert-butylate; ammonia; hydrogen; sodium hydrogencarbonate; potassium carbonate; copper(l) iodide; palladium on activated charcoal; rac-diaminocyclohexane; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; water; ethyl acetate; acetonitrile;

Reference yield:

: 1073633-84-7
6-(methyloxy)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one

: 1073633-91-6
phenylmethyl 4-[6-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5,6,7,8-tetrahydro-2-quinazolinyl]-6-(methyloxy)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / water; ethyl acetate / 0.75 h / 20 °C

2: potassium carbonate / copper(l) iodide; rac-diaminocyclohexane / 1,4-dioxane / 10 h / 125 °C

With sodium hydrogencarbonate; potassium carbonate; copper(l) iodide; rac-diaminocyclohexane; In 1,4-dioxane; water; ethyl acetate;