2-(3-Methoxy-phenyl)-succinonitrile

Base Information

Chemical Name:2-(3-Methoxy-phenyl)-succinonitrile
CAS No.:120238-17-7
Molecular Formula:C₁₁H₁₀N₂O
Molecular Weight:186.213
Hs Code.:
European Community (EC) Number:683-003-5
Nikkaji Number:J3.483.409A

Synonyms:AKOS022301001;2-(3-METHOXY-PHENYL)-SUCCINONITRILE

Suppliers and Price of 2-(3-Methoxy-phenyl)-succinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3-Methoxy-phenyl)-succinonitrile

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C(CC#N)C#N

Technology Process of 2-(3-Methoxy-phenyl)-succinonitrile

There total 3 articles about 2-(3-Methoxy-phenyl)-succinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 7677-24-9
trimethylsilyl cyanide

: 3179-09-7
1-methoxy-3-(2-nitrovinyl)benzene

: 120238-17-7
3-cyano-3-(3-methoxyphenyl)propanenitrile

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/chem.201404780

Reference yield: 76.0%

: 24393-44-0,19098-69-2
2-cyano-3-(3-methoxyphenyl)acrylic acid ethyl ester

: 544-92-3
copper(I) cyanide

: 120238-17-7
3-cyano-3-(3-methoxyphenyl)propanenitrile

Guidance literature:: In ethanol; chloroform; water; for 80h; Heating;
DOI:10.1002/jhet.5570250527

Reference yield:

: 591-31-1
3-methoxy-benzaldehyde

: 120238-17-7
3-cyano-3-(3-methoxyphenyl)propanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / piperidine / toluene / Heating; azeotropic water removal

2: 76 percent / CHCl₃; ethanol; H₂O / 80 h / Heating

With piperidine; In ethanol; chloroform; water; toluene;
DOI:10.1002/jhet.5570250527