uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside

Base Information

• Chemical Name: uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside
• CAS No.: 212137-54-7
• Molecular Formula: C₁₇H₂₄F₃N₃O₁₇P₂
• Molecular Weight: 661.33
• Mol file: 212137-54-7.mol

Synonyms:uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside

Chemical Property of uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside

There total 1 articles about uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

uridine 5'-monophosphate morpholidate (27908-36-7) + Phosphoric acid mono-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-3-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-2-yl] ester (212137-48-9) → uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside (212137-54-7)

Guidance literature:

With 1H-tetrazole; Tri-n-octylamine; for 70h;

DOI:10.1021/ja0555217

Reference yield: 98.0%

uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside (212137-54-7) → uridine 5'-(2-amino-2-deoxy-α-D-glucopyranosyl)-diphosphate (1109-79-1,15595-27-4,17479-04-8,17479-06-0,19014-01-8,26234-91-3,55660-11-2)

Guidance literature:

With water; potassium carbonate; In methanol; at 20 ℃; pH=9.5;

DOI:10.1039/c1cc14034e

Reference yield: 97.0%

uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside (212137-54-7) + C22H32F7NO13 (1582775-57-2) → C30H42F10N2O18 (1582775-63-0)

Guidance literature:

With Escherichia coli glycosyltransferase; manganese(ll) chloride; In aq. buffer; at 20 ℃; pH=7.2; Enzymatic reaction;

DOI:10.1021/ol500738g

upstream raw materials:

uridine 5'-monophosphate morpholidate

Phosphoric acid mono-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-3-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-2-yl] ester

Downstream raw materials:

uridine 5'-(2-amino-2-deoxy-α-D-glucopyranosyl)-diphosphate

uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside

uridine 5'-diphospho-2-(1,1'-biphenyl-4-yl)acetamido-2-deoxy-α-D-glucopyranoside

C₃₀H₄₂F₁₀N₂O₁₈