uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside

Base Information

• Chemical Name: uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside
• CAS No.: 1338332-56-1
• Molecular Formula: C₂₃H₃₁N₃O₁₇P₂
• Molecular Weight: 683.457
• Mol file: 1338332-56-1.mol

Synonyms:uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside

Chemical Property of uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside

There total 5 articles about uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

uridine 5'-(2-amino-2-deoxy-α-D-glucopyranosyl)-diphosphate (1109-79-1,15595-27-4,17479-04-8,17479-06-0,19014-01-8,26234-91-3,55660-11-2) + phenylacetyl chloride (103-80-0) → uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside (1338332-56-1)

Guidance literature:

With sodium hydrogencarbonate; In water; acetonitrile; at 0 ℃; for 4h;

DOI:10.1039/c1cc14034e

Reference yield:

uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside (212137-54-7) → uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside (1338332-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: water; potassium carbonate / methanol / 20 °C / pH 9.5

2: sodium hydrogencarbonate / water; acetonitrile / 4 h / 0 °C

With water; sodium hydrogencarbonate; potassium carbonate; In methanol; water; acetonitrile;

DOI:10.1039/c1cc14034e

Reference yield:

phenylacetic acid (103-82-2) → uridine 5'-diphospho-2-phenylacetamido-2-deoxy-α-D-glucopyranoside (1338332-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C

2: sodium hydrogencarbonate / water; acetonitrile / 4 h / 0 °C

With oxalyl dichloride; sodium hydrogencarbonate; N,N-dimethyl-formamide; In dichloromethane; water; acetonitrile;

DOI:10.1039/c1cc14034e

upstream raw materials:

uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside

phenylacetic acid

2-trifluoroacetamido-2-deoxy-α,β-D-glucopyranose

UTP