1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

Base Information

Chemical Name:1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane
CAS No.:123330-89-2
Molecular Formula:C₃₂H₄₂N₂O₁₂
Molecular Weight:646.692
Hs Code.:

1-<2-<Bis<(methoxycarbonyl)methyl>amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-<bis<(methoxycarbonyl)methyl>amino>-5-methylphenoxy>ethane

Synonyms:1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

Suppliers and Price of 1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of 1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

There total 8 articles about 1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 96-32-2
bromoacetic acid methyl ester

: 123330-88-1
1-<2-Amino-5-(tert-butoxycarbonyl)phenoxy>-2-(2-amino-5-methylphenoxy)ethane

: 123330-89-2
1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

Guidance literature:: With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; at 125 ℃; for 48h;
DOI:10.1021/ja00202a042

Reference yield:

: 619-14-7
3-hydroxy-4-nitro-benzoic acid

: 123330-89-2
1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) pyridine; 2.) H₂O / 1.) 100 deg C, 30 min

2: SOCl₂, DMF / 0.25 h / Heating

3: pyridine / CHCl₃ / Heating

4: 45percent aq. KOH / methanol / 0.5 h

5: 92 percent / K₂CO₃, N-methylpyrrolidinone / 0.17 h / 140 °C

6: 81 percent / H₂ / 5percent Pd/C / ethyl acetate; ethanol / 1 h / Ambient temperature

7: 78 percent / 1,8-bis(dimethylamino)naphthalene / 48 h / 125 °C

With pyridine; 1-methyl-pyrrolidin-2-one; potassium hydroxide; thionyl chloride; water; hydrogen; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; potassium carbonate; N,N-dimethyl-formamide; palladium on activated charcoal; In methanol; ethanol; chloroform; ethyl acetate;
DOI:10.1021/ja00202a042

Reference yield:

: 51257-24-0
3-Acetoxy-4-Nitrobenzoic Acid

: 123330-89-2
1-<2-amino>-5-(tert-butoxycarbonyl)phenoxy>-2-<2-amino>-5-methylphenoxy>ethane

Guidance literature:: Multi-step reaction with 6 steps

1: SOCl₂, DMF / 0.25 h / Heating

2: pyridine / CHCl₃ / Heating

3: 45percent aq. KOH / methanol / 0.5 h

4: 92 percent / K₂CO₃, N-methylpyrrolidinone / 0.17 h / 140 °C

5: 81 percent / H₂ / 5percent Pd/C / ethyl acetate; ethanol / 1 h / Ambient temperature

6: 78 percent / 1,8-bis(dimethylamino)naphthalene / 48 h / 125 °C

With pyridine; 1-methyl-pyrrolidin-2-one; potassium hydroxide; thionyl chloride; hydrogen; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; potassium carbonate; N,N-dimethyl-formamide; palladium on activated charcoal; In methanol; ethanol; chloroform; ethyl acetate;
DOI:10.1021/ja00202a042