Technology Process of 4,4,5,5-tetramethyl-2-(2-butyl-1-cyclohexylidenethenyl-2-yl)-[1,3,2]dioxaborolane
There total 5 articles about 4,4,5,5-tetramethyl-2-(2-butyl-1-cyclohexylidenethenyl-2-yl)-[1,3,2]dioxaborolane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
gold-nanoparticles supported on TiO2;
In
1,4-dioxane;
at 60 ℃;
for 0.5h;
DOI:10.1021/acscatal.0c03771
- Guidance literature:
-
With
titanium(IV) isopropylate; tetrakis(acetonitrile)copper(II) tetrafluoroborate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
tert-butyl methyl ether;
at 60 ℃;
for 24h;
regioselective reaction;
Glovebox;
Inert atmosphere;
DOI:10.1021/acs.orglett.7b00256
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 4 h / -78 - 20 °C / Inert atmosphere
2.1: tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 16 h / 50 °C / Glovebox; Inert atmosphere; Sealed tube
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); n-butyllithium;
In
tetrahydrofuran;
3.1: |Suzuki-Miyaura Coupling;
DOI:10.1021/ja502792s
