Technology Process of Methyl 6-azido-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside
There total 3 articles about Methyl 6-azido-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; triphenylphosphine;
In
toluene;
for 0.5h;
Ambient temperature;
DOI:10.1021/jo00108a030
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) n-BuLi, MgBr2 / 1.) hexane, Et2O, -5 deg C, 30 min, 2.) -30 deg C to r.t.
2: 96 percent / Bu4NF / tetrahydrofuran / 0.25 h / Ambient temperature
3: 75 percent / Ph3P, Zn(N3)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature
With
n-butyllithium; zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triphenylphosphine; magnesium bromide;
In
tetrahydrofuran; toluene;
DOI:10.1021/jo00108a030
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / Bu4NF / tetrahydrofuran / 0.25 h / Ambient temperature
2: 75 percent / Ph3P, Zn(N3)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature
With
zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triphenylphosphine;
In
tetrahydrofuran; toluene;
DOI:10.1021/jo00108a030
