Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Base Information

Chemical Name:Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside
CAS No.:161147-40-6
Molecular Formula:C₃₂H₃₅NO₆
Molecular Weight:529.633
Hs Code.:

Synonyms:Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Suppliers and Price of Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

There total 4 articles about Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83051-88-1
methyl 6-aldehydo-2,3,4-tri-O-benzyl-α-D-glucopyranoside

: 161147-40-6
Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) n-BuLi, MgBr₂ / 1.) hexane, Et₂O, -5 deg C, 30 min, 2.) -30 deg C to r.t.

2: 96 percent / Bu₄NF / tetrahydrofuran / 0.25 h / Ambient temperature

3: 75 percent / Ph₃P, Zn(N₃)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature

4: 1,3-propanedithiol, Et₃N / methanol / 24 h / 45 °C

5: pyridine / 3 h / Ambient temperature

With pyridine; 1.3-propanedithiol; n-butyllithium; zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; magnesium bromide; In tetrahydrofuran; methanol; toluene;
DOI:10.1021/jo00108a030

Reference yield:

: 103597-22-4
methyl-2,3,4-tri-O-benzyl-7,7,8,8-tetradehydro-7,8-dideoxy-β-L-glycero-D-gluco-octopyranoside

: 161147-40-6
Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / Ph₃P, Zn(N₃)2*2py, diisopropyl azodicarboxylate / toluene / 0.5 h / Ambient temperature

2: 1,3-propanedithiol, Et₃N / methanol / 24 h / 45 °C

3: pyridine / 3 h / Ambient temperature

With pyridine; 1.3-propanedithiol; zinc azide * 2 pyridine; di-isopropyl azodicarboxylate; triethylamine; triphenylphosphine; In methanol; toluene;
DOI:10.1021/jo00108a030

Reference yield:

: 161147-36-0
Methyl 6-azido-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

: 161147-40-6
Methyl 6-(N-acetylamino)-2,3,4-tri-O-benzyl-6,7,8-trideoxy-D-glycero-α-D-gluco-oct-7-ynopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 1,3-propanedithiol, Et₃N / methanol / 24 h / 45 °C

2: pyridine / 3 h / Ambient temperature

With pyridine; 1.3-propanedithiol; triethylamine; In methanol;
DOI:10.1021/jo00108a030