1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine

Base Information

• Chemical Name: 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine
• CAS No.: 370559-34-5
• Molecular Formula: C₂₂H₂₇NO₅
• Molecular Weight: 385.46
• Mol file: 370559-34-5.mol

Synonyms:1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine

Chemical Property of 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine

There total 2 articles about 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3-phenyl-5-yl-pyrrolidin-3-yl)-ethanol (52423-63-9) + (+)-3-phenyl-3-(2-hydroxy-ethyl)-pyrrolidine (R,R)-di-p-anisoyltartaric acid salt (1133464-33-1,178371-24-9,178371-26-1) + 3,4,5-(trimethoxy)benzoyl chloride (7169-07-5) → 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (370559-34-5)

Guidance literature:

With potassium carbonate; In water; acetone;

Reference yield:

2-(3-phenyl-5-yl-pyrrolidin-3-yl)-ethanol (52423-63-9) + 3,4,5-(trimethoxy)benzoyl chloride (7169-07-5) → 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (370559-34-5)

Guidance literature:

With potassium carbonate; In water; acetone;

Reference yield:

1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (370559-34-5) → 1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidine (192941-21-2)

Guidance literature:

upstream raw materials:

2-(3-phenyl-5-yl-pyrrolidin-3-yl)-ethanol

(+)-3-phenyl-3-(2-hydroxy-ethyl)-pyrrolidine (R,R)-di-p-anisoyltartaric acid salt

3,4,5-(trimethoxy)benzoyl chloride

Downstream raw materials:

1-(2,3,4-trimethoxybenzoyl)-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidine