Ethyl aminooxyacetate hydrochloride

Base Information

• Chemical Name: Ethyl aminooxyacetate hydrochloride
• CAS No.: 3919-73-1
• Molecular Formula: C4H9NO3
• Molecular Weight: 155.581
• Mol file: 3919-73-1.mol

Synonyms:Ethyl aminooxyacetate hydrochloride;Ethyl aminooxyactate hydrochloride;Ethyl aminoxyacetate hydrochloride;NSC 12903;NSC 45077;(2-ethoxy-2-oxoethoxy)azanium;chloride;3919-73-1;Acetic acid, (aminooxy)-, ethyl ester, hydrochloride;Acetic acid, 2-(aminooxy)-, ethyl ester, hydrochloride;ACETIC ACID, 2-AMINOOXY-, ETHYL ESTER, HYDROCHLORIDE;C4H9NO3.ClH;Acetic acid, (aminooxy)-, ethyl ester, hydrochloride (8CI)

Chemical Property of Ethyl aminooxyacetate hydrochloride

Chemical Property:

• Vapor Pressure: 0.456mmHg at 25°C
• Boiling Point: 193.8°Cat760mmHg
• Flash Point: 88.1°C
• PSA: 61.55000
• Density: g/cm³
• LogP: 0.94210
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 155.0349209
• Heavy Atom Count: 9
• Complexity: 73.7

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)CO[NH3+].[Cl-]

Technology Process of Ethyl aminooxyacetate hydrochloride

There total 3 articles about Ethyl aminooxyacetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-(aminooxy)acetic acid hemihydrochloride + ethanol (64-17-5) → O-Ethoxycarbonylmethylhydroxylamine hydrochloride (3919-73-1)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol203213f

Reference yield: 91.0%

ethyl bromoacetate (105-36-2) → O-Ethoxycarbonylmethylhydroxylamine hydrochloride (3919-73-1)

Guidance literature:

Reference yield: 76.0%

N-(ethoxy carbonyl methoxy)-phthalimide (5251-81-0) → O-Ethoxycarbonylmethylhydroxylamine hydrochloride (3919-73-1)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 24h;

DOI:10.1021/jm030219z

upstream raw materials:

N-(ethoxy carbonyl methoxy)-phthalimide

ethyl bromoacetate

ethanol

Downstream raw materials:

O-(D,L-Phenylalanylamino)-hydroxyessigsaeure-ethylester

O-(Benzyloxycarbonyl-DL-alanylamino)-hydroxy-essigsaeure-ethylester

O-(Benzyloxycarbonyl-D,L-phenylalanylamino)-hydroxy-essigsaeure-ethylester

pyridine hydrochloride

Refernces

• 1、 Elokdah, Hassan,Sulkowski, Theodore S.,Abou-Gharbia, Magid,Butera, John A.,Chai, Sie-Yearl,McFarlane, Geraldine R.,McKean, Mar-Lee,Babiak, John L.,Adelman, Steven J.,Quinet, Elaine M.. "Design, Synthesis, and Biological Evaluation of Thio-Containing Compounds with Serum HDL-Cholesterol-Elevating Properties". . p. 681 - 695. Retrieved 2007/10/03.