di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate

Base Information

• Chemical Name: di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate
• CAS No.: 1357009-14-3
• Molecular Formula: C₂₅H₄₁N₃O₄
• Molecular Weight: 447.618
• Mol file: 1357009-14-3.mol

Synonyms:di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate

Chemical Property of di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate

There total 6 articles about di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl bromide (100-39-0) + 1,4-bis(tert-butoxycarbonylmethyl)-1,4,7-triazacyclononane (174137-97-4) → di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate (1357009-14-3)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 48h;

DOI:10.1039/c9dt00211a

Reference yield: 63.0%

bromoacetic acid tert-butyl ester (5292-43-3) + 1-benzyl-[1,4,7]-triazacyclononane (174912-95-9) → di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate (1357009-14-3)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 96h;

DOI:10.1021/acs.inorgchem.5b01719

Reference yield:

1,4,7-triazacyclononane (4730-54-5) → di-tert-butyl 2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetate (1357009-14-3)

Guidance literature:

Multi-step reaction with 2 steps

1: chloroform / 24.66 h / 20 °C

2: potassium carbonate / tetrahydrofuran / 12 h / 20 °C

With potassium carbonate; In tetrahydrofuran; chloroform;

DOI:10.1039/c1cc13151f

upstream raw materials:

bromoacetic acid tert-butyl ester

benzyl bromide

1,4-bis(tert-butoxycarbonylmethyl)-1,4,7-triazacyclononane

1,4,7-triazacyclononane

Downstream raw materials:

1,4-bis(tert-butoxycarbonylmethyl)-1,4,7-triazacyclononane

2,2′-(7-benzyl-1,4,7-triazonane-1,4-diyl)diacetic acid