methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate

Base Information

• Chemical Name: methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate
• CAS No.: 1013657-91-4
• Molecular Formula: C₁₉H₂₉N₅O₃
• Molecular Weight: 375.471
• Mol file: 1013657-91-4.mol

Synonyms:methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate

Chemical Property of methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate

There total 1 articles about methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

dimethyl (E)-2-(pyrrolidin-1-yldiazenyl)terephthalate (1013657-89-0) + N,N-diethylethylenediamine (100-36-7) → methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate (1013657-91-4)

Guidance literature:

N,N-diethylethylenediamine; With Al(CH₃)2; In hexane; dichloromethane; at 0 - 5 ℃; for 2h;

dimethyl (E)-2-(pyrrolidin-1-yldiazenyl)terephthalate; In hexane; dichloromethane; for 77h; Further stages.; Heating;

DOI:10.1021/jm701419g

Reference yield: 12.0%

methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate (1013657-91-4) → methyl 4-(((2-diethylamino)ethyl)carbamoyl)-2-iodobenzoate (1013657-92-5)

Guidance literature:

With trifluoroacetic acid; potassium iodide; In acetonitrile; at 20 ℃;

DOI:10.1021/jm701419g

Reference yield:

methyl (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate (1013657-91-4) → lithium (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate (1013657-95-8)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 1h;

DOI:10.1021/jm701419g

upstream raw materials:

dimethyl (E)-2-(pyrrolidin-1-yldiazenyl)terephthalate

N,N-diethylethylenediamine

Downstream raw materials:

methyl 4-(((2-diethylamino)ethyl)carbamoyl)-2-iodobenzoate

lithium (E)-4-(((2-diethylamino)ethyl)carbamoyl)-2-(pyrrolidin-1-yldiazenyl)benzoate