14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate

Base Information

Chemical Name:14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate
CAS No.:397250-01-0
Molecular Formula:C₃₈H₄₈O₁₃Si
Molecular Weight:740.877
Hs Code.:
Mol file:397250-01-0.mol

Synonyms:13-dehydro-14β-hydroxy-7-triethylsilylbaccatin III 1,14-carbonate

Suppliers and Price of 14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
14β-Hydroxy-13-oxo-7-O-(triethylsilyl)BaccatinIII1,14-Carbonate
2.5mg
$ 165.00

Medical Isotopes, Inc.
14β-Hydroxy-13-oxo-7-O-(triethylsilyl)BaccatinIII1,14-Carbonate
25 mg
$ 2200.00

Total 2 raw suppliers

Chemical Property of 14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate

Chemical Property:

Storage Temp.:Refrigerator
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

14β-Hydroxy-13-oxo-7-O-(triethylsilyl)BaccatinIII1,14-Carbonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate is used in the preparation of Hydroxybaccatin III Carbonate derivatives.

Technology Process of 14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate

There total 5 articles about 14β-Hydroxy-13-oxo-7-O-(triethylsilyl) Baccatin III 1,14-Carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 75-44-5
phosgene

: 370110-84-2
13-dehydro-14β-hydroxy-7-triethylsilylbaccatin III

: 397250-01-0
13-dehydro-14β-hydroxy-7-triethylsilylbaccatin III 1,14-carbonate

Guidance literature:: With pyridine; In dichloromethane; toluene; at 20 ℃; for 1.08333h;

Reference yield:

: 75-44-5
phosgene

: 370110-84-2
13-dehydro-14β-hydroxy-7-triethylsilylbaccatin III

: C₃₈H₄₈O₁₃Si

: 397250-01-0
13-dehydro-14β-hydroxy-7-triethylsilylbaccatin III 1,14-carbonate

Guidance literature:: With triethylamine; In dichloromethane; toluene; at 20 ℃; for 1.08333h;

Reference yield:

: 150665-56-8
7-O-triethylsilyl-13-keto baccatin III

: 397250-01-0
13-dehydro-14β-hydroxy-7-triethylsilylbaccatin III 1,14-carbonate

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / (1S)-(10-camphorsulfonyl)oxaziridine; t-BuOK; DMPU / tetrahydrofuran / -65 - -60 °C

2: pyridine / CH₂Cl₂; toluene / 0.33 h / 0 °C

With pyridine; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; potassium tert-butylate; (1S)-(+)-(10-camphorsulfonyl)-oxaziridine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo0347112