7-Triethylsilyl-13-oxobaccatin III

Base Information

Chemical Name:7-Triethylsilyl-13-oxobaccatin III
CAS No.:150665-56-8
Molecular Formula:C₃₇H₅₀O₁₁Si
Molecular Weight:698.883
Hs Code.:
Mol file:150665-56-8.mol

Synonyms:7-O-triethylsilyl-13-keto baccatin III

Suppliers and Price of 7-Triethylsilyl-13-oxobaccatin III

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Triethylsilyl-13-oxobaccatinIII
50mg
$ 1190.00

Medical Isotopes, Inc.
7-Triethylsilyl-13-oxobaccatinIII
5 mg
$ 650.00

Total 1 raw suppliers

Chemical Property of 7-Triethylsilyl-13-oxobaccatin III

Chemical Property:

Melting Point:212 °C
Boiling Point:721.7±60.0 °C(Predicted)
PKA:11.98±0.70(Predicted)
Density:1.24±0.1 g/cm3(Predicted)
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:: 7-Triethylsilyl-13-oxobaccatinIII ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 7-Triethylsilyl-13-oxobaccatin III is used in the preparation of taxol analogs as antineoplastic agents and taxoids derivatives useful due to their ability to activate murine macrophages and inhibit the growth of macrophage-like cells. Baccatin III (B101000) derivative, used in the preparation of taxol analogs as antineoplastic agents and taxoids derivatives useful due to their ability to activate murine macrophages and inhibit the growth of macrophage-like cells.

Technology Process of 7-Triethylsilyl-13-oxobaccatin III

There total 14 articles about 7-Triethylsilyl-13-oxobaccatin III which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 115437-21-3
7-(triethylsilyl)baccatin III

: 150665-56-8
7-O-triethylsilyl-13-keto baccatin III

Guidance literature:: With dipyridinium dichromate; In dichloromethane; at 20 ℃; for 1.5h;
DOI:10.1039/c3ob40407b

Reference yield: 85.0%

: 108-24-7
acetic anhydride

: 155588-21-9
7-triethylsilyl-13-dehydro-10-deacetylbaccatin III

: 150665-56-8
7-O-triethylsilyl-13-keto baccatin III

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1016/S0968-0896(03)00181-0

Reference yield: 81.0%

: 474766-89-7
13-epi-7-O-(triethylsilyl)baccatin III

: 150665-56-8
7-O-triethylsilyl-13-keto baccatin III

Guidance literature:: With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jo011183q