N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Base Information

Chemical Name:N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine
CAS No.:340721-61-1
Molecular Formula:C₃₇H₅₁N₅O₆Si₂
Molecular Weight:718.013
Hs Code.:

N<sup>6</sup>-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Synonyms:N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Suppliers and Price of N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

There total 5 articles about N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 98-88-4
benzoyl chloride

: 340721-56-4
N⁶-benzoyl-2'-deoxy-8-(hydroxymethyl)-3',5'-bis-O-(triethylsilyl)adenosine

: 340721-61-1
N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at -10 ℃; for 3h;
DOI:10.1002/1522-2675(20010321)84:3<594::AID-HLCA594>3.0.CO;2-9

Reference yield:

: 994-30-9
triethylsilyl chloride

: 340721-61-1
N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 88 percent / imidazole / dimethylformamide / 16 h / 23 °C

2.1: LDA / tetrahydrofuran; hexane / 2.5 h / -70 °C

3.1: AcOH / tetrahydrofuran / 23 °C

3.2: NaBH₄ / ethanol; tetrahydrofuran; acetic acid / 0.42 h / 23 °C

4.1: 73 percent / iPr₂NEt / CH₂Cl₂ / 3 h / -10 °C

With 1H-imidazole; acetic acid; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/1522-2675(20010321)84:3<594::AID-HLCA594>3.0.CO;2-9

Reference yield:

: 4546-72-9
N₆-benzoyl-2'-deoxyadenosine

: 340721-61-1
N⁶-benzoyl-8-[(benzoyloxy)methyl]-2'-deoxy-3',5'-bis-O-(triethylsilyl)adenosine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 88 percent / imidazole / dimethylformamide / 16 h / 23 °C

2.1: LDA / tetrahydrofuran; hexane / 2.5 h / -70 °C

3.1: AcOH / tetrahydrofuran / 23 °C

3.2: NaBH₄ / ethanol; tetrahydrofuran; acetic acid / 0.42 h / 23 °C

4.1: 73 percent / iPr₂NEt / CH₂Cl₂ / 3 h / -10 °C

With 1H-imidazole; acetic acid; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/1522-2675(20010321)84:3<594::AID-HLCA594>3.0.CO;2-9