pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate

Base Information

• Chemical Name: pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate
• CAS No.: 1214284-55-5
• Molecular Formula: C₃₁H₄₂N₄O₇
• Molecular Weight: 582.697

Synonyms:pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate

Chemical Property of pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate

There total 1 articles about pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

pentyl (S)-4-(2-amino-4-tert-butoxycarbonylbutyryl)piperazine-1-carboxylate (1198783-32-2) + 4-hydroxy-6-phenylpyridine-2-carboxylic acid (78296-37-4) → pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate (1214284-55-5)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; In dichloromethane; N,N-dimethyl-formamide; for 16h;

DOI:10.1021/jm901518t

Reference yield: 92.0%

pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate (1214284-55-5) → (4S)-4-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxo-5-(4-[(pentyloxy)carbonyl]piperazin-1-yl)pentanoic acid (1214285-18-3)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

DOI:10.1021/jm901518t

Reference yield: 78.0%

trifluoromethylsulfonic anhydride (358-23-6) + pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate (1214284-55-5) → pentyl 4-[(2S)-5-tert-butoxy-5-oxo-2-([(6-phenyl-4-([(trifluoromethyl)sulfonyl]oxy)pyridin-2-yl)carbonyl]amino)pentanoyl]piperazine-1-carboxylate (1214285-92-3)

Guidance literature:

With pyridine; at 20 ℃; Cooling with ice;

DOI:10.1021/jm901518t

upstream raw materials:

pentyl (S)-4-(2-amino-4-tert-butoxycarbonylbutyryl)piperazine-1-carboxylate

4-hydroxy-6-phenylpyridine-2-carboxylic acid

Downstream raw materials:

(4S)-4-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxo-5-(4-[(pentyloxy)carbonyl]piperazin-1-yl)pentanoic acid

pentyl 4-[(2S)-2-(([4-((1-[(benzyloxy)carbonyl]piperidin-4-yl)-oxy)-6-phenylpyridin-2-yl]carbonyl)amino)-5-tert-butoxy-5-oxopentanoyl]piperazine-1-carboxylate

pentyl 4-[(2S)-5-tert-butoxy-5-oxo-2-([(6-phenyl-4-([(trifluoromethyl)sulfonyl]oxy)pyridin-2-yl)carbonyl]amino)pentanoyl]piperazine-1-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1214284-55-5 pentyl 4-((2S)-5-tert-butoxy-2-([(4-hydroxy-6-phenylpyridin-2-yl)carbonyl]amino)-5-oxopentanoyl)piperazine-1-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send