3-AMINOHEXANE

Base Information

• Chemical Name: 3-AMINOHEXANE
• CAS No.: 16751-58-9
• Molecular Formula: C6H15 N
• Molecular Weight: 101.192
• Mol file: 16751-58-9.mol

Synonyms:Butylamine,1-ethyl- (8CI); 3-Aminohexane; 3-Hexylamine

Chemical Property of 3-AMINOHEXANE

Chemical Property:

• Vapor Pressure: 16mmHg at 25°C
• Melting Point: -40.7°C (estimate)
• Refractive Index: 1.4200
• Boiling Point: 119.3°Cat760mmHg
• PKA: 11.00±0.35(Predicted)
• Flash Point: 25.2°C
• PSA: 26.02000
• Density: 0.768g/cm³
• LogP: 2.22410

Purity/Quality:

98%min ^*data from raw suppliers

HEXAN-3-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMINOHEXANE

There total 14 articles about 3-AMINOHEXANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

→ 3-aminohexane (16751-58-9)

Guidance literature:

Reference yield: 38.0%

n-hexan-3-one (589-38-8) → 3-aminohexane (16751-58-9)

Guidance literature:

With ammonium acetate; sodium cyanoborohydride; at 20 ℃; for 24h;

Reference yield:

hexane (110-54-3) → 1-Methyl-pentylamin (68107-05-1) + hexan-1-amine (111-26-2) + 3-aminohexane (16751-58-9)

Guidance literature:

hexane; With cerium(III) chloride; 1,1,1-trichloroethanol; di-tert-butyl-diazodicarboxylate; tetrabutyl-ammonium chloride; In acetonitrile; at 20 ℃; for 12h; Irradiation; Inert atmosphere; Sealed tube;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

With hydrogen; In methanol; for 12h; Reagent/catalyst;

DOI:10.1021/jacs.0c00212

upstream raw materials:

propyl ethyl ketoxime

n-hexan-3-one

formamide

cis-3-hexene

Downstream raw materials:

2,5-Dimethyl-4-phenyl-3-pyrrolcarbonsaeure-ethylester

1-phenylhexan-3-amine

Refernces

• 1、 An, Qing,Chen, Yuegang,Liu, Weimin,Pan, Hui,Wang, Xin,Wang, Ziyu,Zhang, Kaining,Zuo, Zhiwei. "Cerium-Catalyzed C-H Functionalizations of Alkanes Utilizing Alcohols as Hydrogen Atom Transfer Agents". supporting information. p. 6216 - 6226. Retrieved 2020/04/27.
• 2、 Guerin, Claire,Bellosta, Veronique,Guillamot, Gerard,Cossy, Janine. "Synthesis of amines from alcohols in a nonepimerizing one-pot sequence - Synthesis of bioactive compounds: Cinacalcet and dexoxadrol". experimental part. p. 2990 - 3000. Retrieved 2012/07/13.