1-Methylpentylamine

Base Information

• Chemical Name: 1-Methylpentylamine
• CAS No.: 68107-05-1
• Molecular Formula: C6H15N
• Molecular Weight: 101.192
• Mol file: 68107-05-1.mol

Synonyms:SEC-HEXYLAMINE;1-Methylpentylamine;2-hexanamine;2-Hexylamine;Pentylamine, 1-methyl-;1-METHYL-N-AMYLAMINE;2-AMINOHEXANE;1-MethylpentylaMine hydrochloride

Chemical Property of 1-Methylpentylamine

Chemical Property:

• Melting Point: -19°C
• Refractive Index: 1.4080
• Boiling Point: 119.64°C (estimate)
• PSA: 26.02000
• Density: 0.7533
• LogP: 2.22410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methylpentylamine

There total 26 articles about 1-Methylpentylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.1%

n-hexan-2-one (591-78-6) + 4-Phenyl-2-butanone (2550-26-7) → (R)-1-methyl-3-phenylpropylamine (937-52-0,22148-77-2,1199266-89-1) + (R)‐2‐aminohexane (5329-79-3,68107-05-1,70095-40-8,70492-67-0)

Guidance literature:

With Candida boidinii formate dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-trans aminase; Lysinibacillus fusiformis leucine dehydrogenase-A₁₁₃G mutant; ammonium formate; nicotinamide adenine dinucleotide; In aq. buffer; at 30 ℃; for 24h; pH=8.8; Catalytic behavior; Green chemistry; Enzymatic reaction;

DOI:10.1021/acs.joc.9b02445

Reference yield: 93.0%

n-hexan-2-one (591-78-6) → (R)‐2‐aminohexane (5329-79-3,68107-05-1,70095-40-8,70492-67-0)

Guidance literature:

With Candida boidinii formate dehydrogenase; Geobacillus stearothermophilus ε‐deaminating L‐lysine dehydrogenase variant 22; nicotinamide adenine dinucleotide; In aq. buffer; at 50 ℃; for 48h; pH=8.5; Reagent/catalyst; Enzymatic reaction;

DOI:10.1002/chem.202003140

Reference yield: 91.0%

(S)-2-hexanol (52019-78-0) → (R)‐2‐aminohexane (5329-79-3,68107-05-1,70095-40-8,70492-67-0)

Guidance literature:

With aminedehydrogenase; ammonia; ammonium chloride; at 30 ℃; for 48h; pH=8.7; enantioselective reaction; Enzymatic reaction;

DOI:10.1126/science.aac9283

upstream raw materials:

1-hexene

CYANAMID

2-Hexyl nitrate

acetic acid

Downstream raw materials:

2-hexylformamide

1-(1-methyl-pentyl)-3,4-diphenyl-pyrrolidine-2,5-dione

(3,4-Dimethyl-2,6-dinitro-phenyl)-(1-methyl-pentyl)-amine

C₁₂H₁₈NO₃S*H⁽¹⁺⁾