2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Base Information

Chemical Name:2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid
CAS No.:1442461-58-6
Molecular Formula:C₂₃H₂₃BO₇
Molecular Weight:422.242
Hs Code.:

Synonyms:2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Suppliers and Price of 2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Chemical Property:

Boiling Point:604.0±55.0 °C(Predicted)
Density:1.31±0.1 g/cm3(Predicted)

Purity/Quality:: 95% ^*data from raw suppliers

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Hazard Codes:

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Technology Process of 2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

There total 7 articles about 2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1442461-54-2
C₂₅H₂₇BO₇

: 1442461-58-6
2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water; at 20 ℃; for 12h;
DOI:10.1002/chem.201203957

Reference yield:

: 105837-04-5
7-bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester

: 1442461-58-6
2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 12 h / 90 °C / Inert atmosphere

2: dihydrogen peroxide / aq. buffer / pH 7.5

3: potassium carbonate / acetonitrile / 24 h / 60 °C

4: sodium hydroxide / methanol; water / 12 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; dihydrogen peroxide; potassium acetate; potassium carbonate; sodium hydroxide; In 1,4-dioxane; methanol; water; acetonitrile; 1: |Miyaura Borylation Reaction;
DOI:10.1002/chem.201203957

Reference yield:

: 1442461-55-3
ethyl 7-((4-methoxybenzyl)oxy)-2-oxo-2H-chromene-3-carboxylate

: 1442461-58-6
2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: potassium superoxide / dimethyl sulfoxide

2: methanol

3: potassium carbonate / acetonitrile / 24 h / 60 °C

4: sodium hydroxide / methanol; water / 12 h / 20 °C

With potassium superoxide; potassium carbonate; sodium hydroxide; In methanol; water; dimethyl sulfoxide; acetonitrile;
DOI:10.1002/chem.201203957