1442461-54-2

Basic information

• Product Name: C₂₅H₂₇BO₇
• Synonyms: C₂₅H₂₇BO₇
• CAS NO: 1442461-54-2
• Molecular Weight: 450.296
• Mol File: 1442461-54-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₇BO₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₇BO₇(1442461-54-2)
• EPA Substance Registry System: C₂₅H₂₇BO₇(1442461-54-2)

Safety Data

• Hazardous Substances Data: 1442461-54-2(Hazardous Substances Data)

Upstream product

• 6093-71-6 7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethyl ester 
• 214360-74-4 2-(3-(bromomethyl)phenyl)-4,4,5,5,-tetramethyl-1,3,2-dioxaborolane 
• 1442461-70-2 C₁₈H₂₁BO₆ 
• 105-53-3 diethyl malonate 
• 138500-85-3 4-bromomethylphenylboronic acid pinacol ester 
• 22532-62-3 4-bromosalicylaldehyde 
• 105837-04-5 7-bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester 
• 1442461-55-3 ethyl 7-((4-methoxybenzyl)oxy)-2-oxo-2H-chromene-3-carboxylate 

Downstream Products

• 1442461-55-3 ethyl 7-((4-methoxybenzyl)oxy)-2-oxo-2H-chromene-3-carboxylate 
• 1442461-56-4 C₂₁H₂₀O₇ 
• 1442461-57-5 C₂₂H₂₂O₈ 
• 1442461-58-6 2-oxo-7-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)-2H-chromene-3-carboxylic acid 
• 1442461-59-7 7-((4-methoxybenzyl)oxy)-2-oxo-2H-chromene-3-carboxylic acid 
• 1442461-60-0 C₁₉H₁₆O₇ 
• 1442461-61-1 C₂₀H₁₈O₈ 
• 6093-71-6 7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethyl ester 
• 1442461-76-8 C₁₈H₁₂O₇ 
• 1084-45-3 ethyl 7-hydroxy-2-oxo-2H-chromene-4-carboxylate 

Relevant articles and documents

A Dual-Response Fluorescent Probe Reveals the H2O2-Induced H2S Biogenesis through a Cystathionine β-Synthase Pathway

The two signaling molecules H2S and H2O2 play key roles in maintaining intracellular redox homeostasis. The biological relationship between H2O2 and H2S remains largely unknown in redox biology. In this study, we rationally designed and synthesized single- and dual-response fluorescent probes for detecting both H2O2 and H2S in living cells. The dual-response probe was shown to be capable of mono- and dual-detection of H2O2 and H2S selectively and sensitively. Detailed bioimaging studies based on the probes revealed that both exogenous and endogenous H2O2 could induce H2S biogenesis in living cells. By using gene-knockdown techniques with bioimaging, the H2S biogenesis was found to be majorly cystathionine β-synthase (CBS)-dependent. Our finding shows the first direct evidence on the biological communication between H2O2 (ROS) and H2S (RSS) in vivo. CBS is responsible: A fluorescent probe with two heads for H2O2 and H2S reveals that both exogenous and endogenous H2O2 molecules can induce endogenous H2S biogenesis on a cystathionine β-synthase (CBS) pathway (see scheme).