2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Base Information

Chemical Name:2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine
CAS No.:127594-29-0
Molecular Formula:C₆₂H₆₆N₂O₁₀Si
Molecular Weight:1027.3
Hs Code.:

Synonyms:2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Suppliers and Price of 2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

There total 9 articles about 2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 127570-64-3
N-acetyl-2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

: 127594-29-0
2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Guidance literature:: With piperidine; In N,N-dimethyl-formamide;
DOI:10.1021/ja00170a055

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 127594-29-0
2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 82 percent / Et₃N / 4-dimethylaminopyridine / CH₂Cl₂ / 9 h / 0 deg C to r.t.

2: 1) Bu₄NI, NaH, / 1) DMF, 2) a) 0 deg C, 1.5 h, b) r.t., 16.5 h

3: 61 percent / NBS / 1 h / Ambient temperature

4: 89 percent / piperidine / dimethylformamide / 3.75 h

With piperidine; N-Bromosuccinimide; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; dmap; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(92)84171-N

Reference yield:

: 100-39-0
benzyl bromide

: 127594-29-0
2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-6-O-tert-butyldiphenylsilyl-α-D-glucopyranosylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Bu₄NI, NaH, / 1) DMF, 2) a) 0 deg C, 1.5 h, b) r.t., 16.5 h

2: 61 percent / NBS / 1 h / Ambient temperature

3: 89 percent / piperidine / dimethylformamide / 3.75 h

With piperidine; N-Bromosuccinimide; tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(92)84171-N