N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Base Information

Chemical Name:N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide
CAS No.:1383852-18-3
Molecular Formula:C₃₃H₃₅N₃O₄S
Molecular Weight:569.725
Hs Code.:

Synonyms:N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

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Chemical Property of N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

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Technology Process of N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

There total 1 articles about N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 541-28-6
isopentyl iodide

: 1383852-17-2
N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)methanesulfonamide

: 1383852-18-3
N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; for 24h;

Reference yield:

: 1383852-18-3
N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

: 1383852-19-4
N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Guidance literature:: With hydrogen; 10 wt% Pd(OH)2 on carbon; In N,N-dimethyl-formamide; for 6h; under 1551.49 Torr;

Reference yield:

: 1383852-18-3
N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

: 1383852-20-7
4-(5-cyclopropyl-3-(1H-imidazol-2-yl)-6-(N-isopentylmethylsulfonamido)benzofuran-2-yl)phenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 10 wt% Pd(OH)2 on carbon / N,N-dimethyl-formamide / 6 h / 1551.49 Torr

2: potassium carbonate / N,N-dimethyl-formamide / 1 h

With hydrogen; potassium carbonate; 10 wt% Pd(OH)2 on carbon; In N,N-dimethyl-formamide;